by California NanoSystems Institute Disruptions in the fission of mitochondria, the structures within cells that make energy, are behind a host of other ailments, including cancer, diabetes and heart disease. Credit: National Institutes of Health As scientists work toward finding a cure for Parkinson’s disease, one line of research that has emerged focuses on mitochondria,...
UNIVERSITÉ DE GENÈVE IMAGE: BIOLOGISTS HAVE CREATED MUTANTS OF THE FER2 HOMOLOG IN MOUSE DOPAMINE NEURONS. CREDIT: (C) ADOBE STOCK Parkinson’s disease is a neurodegenerative disorder characterized by the destruction of a specific population of neurons: the dopaminergic neurons. The degeneration of these neurons prevents the transmission of signals controlling specific muscle movements and leads...
by Queen Mary, University of London Credit: Pixabay/CC0 Public Domain Hearing loss and epilepsy are early features of Parkinson’s, according to pioneering new research from Queen Mary University of London—the first UK study of the condition in such a diverse population, published today in JAMA Neurology. Queen Mary researchers funded by Bart’s Charity used electronic primary...
In a small lab decorated with a poster of colorful MRI brain scans, Elizabeth Stegemoller hits a stopwatch to record how long a participant in her study can sustain the vowel sound “ah” before taking a breath. They run through this a few times before Stegemoller moves on to measure the participant’s range of pitch...
by Naomi Cocks, The Conversation Credit: Shutterstock Imagine not wanting to leave your house because of fear you would drool. That’s the choice many people with Parkinson’s disease confront every day. Parkinson’s disease is the second most common neurodegenerative condition in Australia after dementia. It’s estimated around 70,000 Australians live with it and one of...
RADBOUD UNIVERSITY MEDICAL CENTER Radboud university medical center launched a platform for people with Parkinson’s Disease. It contains seven gait strategies, which can help the patients with walking. The website will be launched on February 2022, 15. This website about walking difficulties in Parkinson’s disease have been developed for people with Parkinson’s, their loved ones, and...
UNIVERSITY OF CINCINNATI IMAGE: JAMES HERMAN, Ph.D., AND HIS COLLEAGUES HAVE DEVELOPED A NEW ANIMAL MODEL THAT CAN DELETE STRESS HORMONE RECEPTORS IN A TARGETED PROCESS THAT DOESN’T AFFECT OTHER PARTS OF THE BRAIN.view more CREDIT: PHOTO/ANDREW HIGLEY/UNIVERSITY OF CINCINNATI Stress can have a negative effect on anyone’s health but presents particular challenges for people with...
by University of Bergen Left: Two views of the 3D structure of TH, with the atomic model generated inside, where the yellow stars point to two of the active centers of TH. Right: The same two views of the 3D structure in the presence of dopamine, which regulate TH by inhibiting activity via the introduction...
by Walter and Eliza Hall Institute of Medical Research Credit: Pixabay/CC0 Public Domain Researchers have solved a decade-long mystery about a critical protein linked to Parkinson’s disease that could help to fast-track treatments for the incurable disease. The research, published in Nature, has for the first time produced a ‘live action’ view of the protein, called PINK1,...
by Public Library of Science G2019S LRRK2 induces iron accumulation in inflammatory microglia in vivo. Credit: Mamais A et al., 2021, PLOS Biology, CC-BY 4.0 (creativecommons.org/licenses/by/4.0/) A common gene mutation for Parkinson’s disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson...
