New research from King’s College London has revealed a previously undiscovered mechanism of cellular communication, between neurons and immune cells, in neuropathic pain. The authors, who published their findings today in Nature Communications, identified a new method of treating neuropathic pain in mice, which could be more safe and effective than current treatments comprising of opioids...
Category: <span>Pharmaceutical Updates</span>
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New meningitis vaccine could prevent 91% of strains, CDC discovers
Tests of a recently-developed meningitis B vaccine reveal that it can prevent nine of its 10 strains Researchers anticipate the shot could prevent 91 percent of strains that affect children in the US It targets the form of meningitis that has historically been the hardest to prevent The vaccine was approved for use on people ages...
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Trigger for most common form of vision loss discovered
Jayakrishna Ambati, M.D., (left) and Nagaraj Kerur, Ph.D., have discovered a crucial trigger for macular degeneration, a condition which robs millions of their sight. The discovery may allow doctors to intervene early to halt the process. Credit: Josh Barney | UVA Health System In a major step forward in the battle against macular degeneration, the...
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The crippling toll of the new Valium that’s ruining the lives of MILLIONS: Rapid rise in prescriptions for GABA drugs is worrying experts
Gabapentinoid (GABA) drugs are increasingly being used to treat nerve pain Around 1.3m Britons now take GABA drugs – a huge rise from 100,000 in 2000 Gabapentinoids prescribed because they were said to be non-addictive It’s now emerging that they are addictive, and can cause withdrawal symptoms With the arthritis in her hip plaguing her...
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Osimertinib improves progression-free survival in Asian EGFR-mutated lung cancer patients
Osimertinib improves progression-free survival compared to standard first line therapy in Asian patients with EGFR-mutated non-small-cell lung cancer (NSCLC), according to the Asian subset analysis of the FLAURA trial presented at the ESMO Asia 2017 Congress, sumultaneously published in The New England Journal of Medicine. EGFR mutations occur in 30-40% of NSCLC in Asian populations compared...
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Pre-diabetes discovery marks step towards precision medicine
High-resolution model of six insulin molecules assembled in a hexamer. Researchers from the University of Sydney’s Charles Perkins Centre have identified three specific molecules that accurately indicate insulin resistance, or pre-diabetes – a major predictor of metabolic syndrome, the collection of medical conditions that include abdominal obesity, high blood pressure and high blood sugar...
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Pneumonia: Treatment with vaccines instead of antibiotics
Mycoplasma bacteria are one of the most common causes of bacterial pneumonia in children. It is still unclear how the disease develops. Researchers from the University Children’s Hospital Zurich and UZH have now demonstrated that there are specific immune cells, so-called B cells, which are crucial for recovery from the infection. The antibodies produced by these...
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Naturally occurring molecule may help prevent and treat atherosclerosis and gum disease
Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood...
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Anti-malaria drug shows promise as Zika virus treatment
La Jolla, Calif., November 17, 2017 — A new collaborative study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC San Diego School of Medicine has found that a medication used to prevent and treat malaria may also be effective for Zika virus. The drug, called chloroquine, has a long history...
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Study may point to new treatment approach for ASD
Using sophisticated genome mining and gene manipulation techniques, researchers at Vanderbilt University Medical Center (VUMC) have solved a mystery that could lead to a new treatment approach for autism spectrum disorder (ASD). Their findings, reported last month in the Journal of Neuroscience, broke new ground: for the first time a variation in a gene called ITGB3...