The US military findings offer yet more hope for potential treatments in future Results were presented at the annual meeting of the International Aids Society However, none of the other patients saw such profound effects, experts said The unnamed patient was treated with ‘broadly neutralising antibodies A HIV patient had the killer virus kept under control for...
Category: <span>Pharmaceutical Updates</span>
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Novel class of antibiotics shows promise against plague, drug-resistant bacteria
Pathogenic bacteria are rapidly developing resistance to the arsenal of microbial therapies—and driving researchers to identify families of therapeutics with new modes of action. Recently, those include antibiotics that inhibit LpxC, an enzyme critical to forming the outer membrane of Gram-negative bacteria. This week in mBio, an international group of scientists report on laboratory experiments suggesting...
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Injection taken every 2 months to control HIV is the ‘next revolution’ in treating the killer virus – scrapping the need for daily drugs
Currently HIV patients have to take antiretroviral drugs each day to prevent Aids But a Phase II trial proved 2 such drugs in an injection offers as much protection The jabs taken every two months slowly release the medication into the blood A team of international scientists found them to work just as well as...
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Ketamine has ‘truly remarkable’ effect on depression and is effective in elderly patients, scientists say
Ketamine can have a “truly remarkable” effect on people with depression, researchers have said after a new study showed promising results among elderly patients. Colleen Loo, a professor at the University of New South Wales in Australia, led the world’s first randomised control trial into the drug’s effect on people over 60 with treatment-resistant depression. “This...
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New drug target could change chronic pain medication
New research has uncovered a target for chronic and pathologic pain, which could lead to better drugs for those affected by pain in the future. A new study has identified a new drug target that could change chronic pain medication going forward. Chronic pain is “the most common cause of long-term disability,” according to the National...
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HOW CLOSE ARE WE TO FINDING A TREATMENT FOR ALZHEIMER’S?
Countries around the world set a goal to find a treatment for Alzheimer’s disease by 2025. But that objective seems increasingly less attainable. There are about 30 drugs for Alzheimer’s disease now in Phase III clinical trials—the last set of experiments drug companies must run to prove their product is safe and effective before obtaining...
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Giving elderly people flu jab with four times the normal dose helps them avoid strokes or a heart attack
A patch placed on the wrist could replace the annual flu jab, research suggests Patches could be sent out in the post, enabling people to vaccinate themselves Experts in Britain said the patches could be particularly useful for children A patch placed on the wrist could replace the annual flu jab, research suggests. In future...
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Clinical trial shows some promise for Duchenne muscular dystrophy drug
The results of an international clinical trial, led in part by a UC Davis School of Medicine expert, have shown that a drug therapy for a severe type of muscular dystrophy holds promise for a subgroup of patients. In a paper just published online in the journal The Lancet, Craig McDonald and colleagues at 53 study sites in...
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A cure for cocaine addiction? Scientists discover how to target the brain to make the drug seem less enticing
Scientists found that rats lacking a brain receptor felt less attached to cocaine Since they had a pre-existing flow of excitement-triggering neurotransmitters, it limited cocaine’s power to induce a high It meant they were less likely to crave the drug after taking it The researchers at the NIDA said this offers a clear path to...
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Antibiotic nanoparticles fight drug-resistant bacteria
Targeted treatment could be used for pneumonia and other bacterial infections Antibiotic resistance is a growing problem, especially among a type of bacteria that are classified as “Gram-negative.” These bacteria have two cell membranes, making it more difficult for drugs to penetrate and kill the cells. Researchers from MIT and other institutions are hoping to...