Highlights Stem cells were rewired via genome engineering to combat inflammation Cells were used to engineer tissues that self-regulate biologic drug production Autoregulated therapy protected tissues from cytokines that drive chronic diseases This approach can form the basis of a cellular vaccine for inflammatory diseases Summary Chronic inflammatory diseases such as arthritis are characterized by...
Category: <span>Pharmaceutical Updates</span>
Researchers ID drug that blocks some blood cancers
A compound identified by Weill Cornell Medicine scientists inhibits the growth of a rare blood cancer found in people with HIV-AIDS. Their research, published May 15 in the Journal of Clinical Investigation, also demonstrates that the compound deters multiple myeloma, another type of blood malignancy. Few effective treatments are available for primary effusion lymphoma(PEL), a subtype...
Scientists develop revolutionary eye drops to treat age-related blindness
Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionise the treatment of one of the leading causes of blindness in the UK. The results of the collaborative research, published today in Investigative Opthamology and Visual Science, could spell the end of painful injections directly into the...
Diabetes drug may help symptoms of autism associated condition
Metformin 500mg tablets. A widely used diabetes medication could help people with a common inherited form of autism, research shows. Scientists found that a drug called metformin improves sociability and reduces symptomatic behaviours in adult mice with a form of Fragile X syndrome. Researchers say that metformin could be repurposed as a therapy for Fragile X syndrome...
Rodents with trouble walking reveal potential treatment approach for most common joint disease
Maintaining the supply of a molecule that helps to nourish cartilage prevented osteoarthritis in animal models of the disease, according to a report published in Nature Communications online May 11. The study is the first, say its authors, to provide evidence that adenosine, a biochemical at the heart of human cellular function, plays another crucial role—keeping on hand...
FDA approves drug to treat ALS
The U.S. Food and Drug Administration today approved Radicava (edaravone) to treat patients with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig’s disease. “After learning about the use of edaravone to treat ALS in Japan, we rapidly engaged with the drug developer about filing a marketing application in the United States,” said Eric...
Charlie Sheen ‘suffered borderline dementia from his old HIV drugs’ – that he says was cured by new drug in a clinical trial
Sheen, 51, revealed his HIV-positive diagnosis in November 2015 In early 2016, he joined a Phase III clinical trial for PRO-140, an intravenous injection that is done once a week, rather than taking daily pills Last year Sheen told Daily Mail Online he experienced a ‘transformation’ after switching from the ‘cocktail of drugs’ to PRO-140...
Traumatic brain injuries may be helped with drug used to treat bipolar disorder
A drug used to treat bipolar disorder and other forms of depression may help to preserve brain function and prevent nerve cells from dying in people with a traumatic brain injury, according to a new Rutgers University study. In research published in Scientific Reports, Rutgers scientists discovered that lithium – used as a mood stabilizer and...
Type 1 diabetes cured in mice using gene therapy
Researchers from the University of Texas Health Science Center in San Antonio have found a way to cure type 1 diabetes in mice. It is hoped that the novel technique – which boosts insulin secretion in the pancreas – will reach human clinical trials in the next 3 years. Researchers have successfully used gene therapy...
Could a CURE for eczema be in sight? Experts finally discover what is triggering the skin condition after years of research
For years, scientists have been unsure as to what triggers the skin condition Those affected have been given creams aimed at relieving their symptoms But new research offers hope of an eventual treatment targeting the root cause They discovered sufferers are missing a vital protein called filaggrin in their skin A cure for eczema could...