by Uppsala University Testicular germ cell tumor-specific mortality in patients with and without prior psychiatric disorders. Cumulative incidence function using non-testicular cancer mortality as competing event for cause-specific testicular cancer mortality in patients with (a) non-seminoma and (b) seminoma with and without history of psychiatric diagnosis. Credit: British Journal of Cancer (2023). DOI: 10.1038/s41416-023-02260-8 A new study by researchers at...
by University of Turku Principal Component Analysis of the serum metabolic profiles of the study participants in early (n = 174) and late pregnancy (n = 159) and prediabetes status at two years postpartum. Blue = no prediabetes and red = prediabetes. Credit: Metabolomics (2023). DOI: 10.1007/s11306-023-01994-z Researchers from the University of Turku in Finland discovered that women who developed prediabetes after pregnancy had aberrations already in...
by Bob Yirka, Medical Xpress ML-based COPD GWAS Manhattan plot via DeepNull. We performed ML-based COPD GWAS where we used the same set of covariates as the Fig. 4 with one additional covariate provided by DeepNull. DeepNull model predicts the ML-based COPD using age, sex, genotype-array, and FEV1/FVC as inputs. The additional DeepNull-covariate is the...
by European Society of Clinical Microbiology and Infectious Diseases Credit: CC0 Public Domain Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year’s European...
by Justin Jackson, Medical Xpress Study and analysis designs. a, Breakdown of the histological disease states among patients with Barrett’s esophagus in the Cambridge selected cross-sectional study, representing the highest disease state for that patient. NDBE, non-dysplastic Barrett’s esophagus. b, The FHCC cohort consisted of 80 patients for whom biopsies were collected prospectively. The cohort...
by Enrique Rivero, University of California, Los Angeles Credit: Pixabay/CC0 Public Domain New UCLA research suggests that a novel machine-learning technique known as “causal forest” was about five times more efficient than the current clinical practice of treating patients with high blood pressure. Under current practice, physicians treat patients with high blood pressure under the assumption that people at...
by Annals of Internal Medicine Credit: Unsplash/CC0 Public Domain In the Annals of Internal Medicine, a general internal medicine physician and a urologist discuss treatment plans for benign prostatic hyperplasia (BPH) and how they would apply their recommendations to a patient who wishes to learn more about his options. Lower urinary tract symptoms due to BPH...
by American Heart Association Credit: CC0 Public Domain Non-biological factors and social determinants of health are important to include in CVD risk assessment for women, particularly for women of diverse races and ethnicities other than white, according to a new American Heart Association scientific statement published today in Circulation, the Association’s flagship, peer-reviewed journal. “Risk assessment is...
By Jane Icke, University of Nottingham Researchers at the University of Nottingham have helped to develop a new tool called “CanPredict,” which is able to identify the people most at risk of developing lung cancer over the next 10 years, and put them forward for screening tests earlier, saving time, money and, most importantly, lives. Featured...
by University of Edinburgh Credit: Unsplash/CC0 Public Domain Analyzing changes to DNA in the blood can improve the ability to predict a person’s risk of developing type 2 diabetes within a decade. Scientists looked at the influence of these changes—known as DNA methylation—alongside other risk factors in almost 15,000 people to predict the likelihood of...
