by Jane Langille, Cornell University Credit: Pixabay/CC0 Public Domain Weill Cornell Medicine investigators have identified definitive biological links between African ancestry and disease processes that affect an aggressive cancer type called triple-negative breast cancer (TNBC). Their analysis of TNBC tumors from a diverse patient population yielded a large set of genes whose expression differed in patients...
Category: <span>Prognostic</span>
Study illuminates precancerous ‘clonal outgrowth’ in blood cells
by Weill Cornell Medical College Credit: CC0 Public Domain A common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may promote these diseases by altering the stem cells’ programming of gene activity and the mix of blood cells they produce, according to a study...
The predictive power of blood: Metabolomic profiling reveals risk of multiple diseases all at once
by Stefanie Seltmann, Berlin Institute of Health in der Charité Details of the metabolomic state model. a) Overview of the residual architecture of the metabolomic state model. 168 circulating metabolomic markers are fed to the shared trunk network to learn a common shared representation. Endpoint-specific head networks then predict the metabolomic state for each endpoint...
Long COVID patients show signs of autoimmune disease a year after infection
by European Lung Foundation Portrait of researcher Dr Manali Mukherjee. Credit: Dr Manali Mukherjee / European Respiratory Society Blood samples drawn from patients with long COVID who are still suffering from fatigue and shortness of breath after a year show signs of autoimmune disease in those patients, according to a study published today in the European...
Smoking may increase odds of Meniere disease in men
For men, smoking is positively related and alcohol consumption is negatively related to the risk for Meniere disease (MD), according to a study published online Aug. 26 in the Journal of Clinical Medicine. So Young Kim, Ph.D., from the CHA University in Seongnam, South Korea, and colleagues examined the association of smoking, alcohol consumption, and obesity with...
Nightmares in middle age linked to dementia risk
by University of Birmingham Credit: CC0 Public Domain People who experience frequent bad dreams in middle age are more likely to be diagnosed with dementia later in life, according to research at the University of Birmingham. A new study, published in The Lancet journal, EClinicalMedicine, suggests nightmares may become prevalent several years or even decades before the characteristic...
Heart attack risk increased among people with HIV and hepatitis C as they aged
by American Heart Association Electron micrographs of hepatitis C virus purified from cell culture. Scale bar is 50 nanometers. Credit: Center for the Study of Hepatitis C, The Rockefeller University. As people with HIV age, their risk of heart attack increases far more if they also have untreated hepatitis C virus, even if their HIV...
Repeated infections associated with increased risk of some neurodegenerative diseases
by Public Library of Science Researchers assess hospital-treated infection and risk of neurodegenerative diseases. Created with Adobe Illustrator. Credit: Jiangwei Sun (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer’s (AD) and Parkinson’s diseases (PD), but not amyotrophic lateral sclerosis (ALS), according to...
Study finds higher complication rate after heart attack in people with autoimmune disease
by American Heart Association Credit: Pixabay/CC0 Public Domain After a heart attack, people with an autoimmune disease were more likely to die, develop heart failure or have a second heart attack compared to people without an autoimmune disease, according to new research published today in the Journal of the American Heart Association. Autoimmune diseases, such as rheumatoid...
Risk factor for developing Alzheimer’s disease increases by 50-80% in older adults who have had COVID-19
by Case Western Reserve University Credit: Pixabay/CC0 Public Domain Older people who were infected with COVID-19 show a substantially higher risk—as much as 50% to 80% higher than a control group—of developing Alzheimer’s disease within a year, according to a study of more than 6 million patients 65 and older. In a study published today...