by Van Andel Research Institute Dysregulated HDAC-related transcriptome precedes the Nnat+/-p-overgrowth. a, Venn diagram of differential gene expression analyses of islets transcriptome of 6 weeks old mice comparing between Nnat+/-p-Heavy, Nnat+/-p-Light morphs and WT littermates. b, GSEA results of HDAC-responsive gene sets between the Nnat+/-p-Light and Nnat+/-p-Heavy morphs, showing a specific enrichment in the latter....
As a result, they may be more likely to develop metabolic disorders and cardiovascular complications in the long term. The intermediate-term and long-term effects of SARS-CoV-2 infections on young adults have scarcely been investigated. Available original research tends to focus on sufferers who were hospitalized, elderly, or who have multiple morbidities. Or, existing research restricts evaluations to...
MURDOCH CHILDRENS RESEARCH INSTITUTE Most children with a condition that causes a temporary weakness or paralysis of the muscles in the face recover without medication within six months, according to a new study. The research, led by the Murdoch Children’s Research Institute and published in Neurology, found the steroid prednisolone does not significantly impact on a child’s recovery...
by McKenzie Ridings, Massachusetts General Hospital Credit: CC0 Public Domain Chronic use of e-cigarettes, commonly known as vaping, can result in progressive small airway obstruction and asthma-like symptoms such as shortness of breath and chest pains, according to researchers at Massachusetts General Hospital (MGH). In the first study to microscopically evaluate the pulmonary tissue of...
by Diabetologia Credit: Pixabay/CC0 Public Domain Men and women who are diagnosed with type 2 diabetes (T2D) aged 40 or younger are far more likely to develop cardiovascular disease (CVD) and die prematurely than those under 40 in the general population, according to new research to be presented at this year’s European Association for the...
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: IT CAN BE USED TO STUDY THE RESISTANCE PROFILE OF PNEUMOCOCCUS EVEN IN THE ABSENCE OF THE ISOLATED STRAINS (PNEUMOCOCCI OBSERVED IN THE MICROSCOPE) CREDIT: IVANA CAMPOS A study published in the journal PLOS ONE could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae,...
by University of Maryland School of Medicine Credit: CC0 Public Domain A person’s blood type may be linked to their risk of having an early stroke, according to a new meta-analysis led by University of Maryland School of Medicine (UMSOM) researchers. Findings were published today in the journal Neurology. The meta-analysis included all available data from...
by Gina Bazer, Northwestern University Credit: Pixabay/CC0 Public Domain Infectious complications continue to affect survivors of childhood cancer many years after initial diagnosis, according to findings from a Northwestern Medicine study published in the Journal of Clinical Oncology. Jenna Rossoff, MD, an instructor of pediatrics in the Division of Hematology, Oncology and Stem Cell Transplantation was...
by Public Library of Science Credit: Pixabay/CC0 Public Domain Researchers have developed a new method to identify people who are at greater genetic risk of developing Alzheimer’s disease before any symptoms appear—which could help speed creation of novel treatments. Manish Paranjpe of the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, United States, and...
Reviewed by Emily Henderson, B.Sc. Sep 1 2022 New research confirms for the first time that ethnicity is a risk factor for developing kidney disease in people with Type 1 diabetes. The study is one of the largest of its type and is published today in Diabetes Care by researchers from King’s College London. The findings also show...
