UNIVERSIDAD COMPLUTENSE DE MADRID UCC-UCM, 26 July 2022. In subjects who are cognitively healthy but have a high genetic risk of developing Alzheimer’s, correlations have been demonstrated between the retina and various brain structures which suffer changes as a result of the disease, such as the entorhinal cortex, the lingual gyrus and the hippocampus. This is the...
Category: <span>Prognostic</span>
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DNA methylation subtype classification can predict outcomes of urothelial carcinoma
by Chinese Academy of Sciences Guadecitabine (SGI-110), a DNA methyltransferase inhibitor, showed therapeutic effects in T24 and UMUC-3 cells. A, B Cell migration capacity with or without SGI-110 treatment was evaluated through wound healing assays. Values are the mean ± SD of eight independent experiments. C, D Cell invasion capacity with or without SGI-110 treatment...
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Severity of PTSD symptoms linked to decreased activity in hippocampus
SOCIETY FOR NEUROSCIENCE IMAGE: FEAR-POTENTIATED STARTLE INTERACTS WITH HIPPOCAMPAL THREAT REACTIVITY IN PREDICTING PTSD AT TWO-WEEKS. CREDIT: TANRIVERDI ET AL., JNEUROSCI 2022 After a traumatic event, people with decreased activity in the hippocampus experience worse PTSD symptoms, according to new research published in JNeurosci. The hippocampus does more than encode new memories — it also takes...
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Blood thickness can predict risk of COVID death
By JERUSALEM POST STAFF Published: JULY 19, 2022 03:44Updated: JULY 19, 2022 16:54 COVID-19 is seen in a blood vessel (Illustrative). (photo credit: TEL AVIV UNIVERSITY) A study out of the Mount Sinai School of Medicine published Monday in The Journal of the American College of Cardiology asserted that patients hospitalized with COVID-19 with high estimated blood viscosity are at...
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PEOPLE WITH UNDERACTIVE THYROID MAY FACE HIGHER DEMENTIA RISK
The risk of developing dementia is even higher for people whose condition required thyroid hormone replacement medication, the researchers report. Hypothyroidism occurs when the thyroid gland doesn’t make enough thyroid hormones, which can slow metabolism. Symptoms include fatigue, weight gain, and sensitivity to cold. “In some cases, thyroid disorders have been associated with dementia symptoms that can...
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Scientists discover genes that affect risk of developing pre-leukemia
by University of Bristol Credit: Wikimedia Commons The discovery of 14 inherited genetic changes which significantly increase the risk of a person developing a symptomless blood disorder associated with the onset of some types of cancer and heart disease is published today in Nature Genetics. The finding, made in one of the largest studies of its...
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Study suggests that c. difficile drives some colorectal cancers
JOHNS HOPKINS MEDICINE Data collected by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing serious diarrheal infections, may also drive colorectal cancer. The findings were published June 9 in Cancer Discovery, and may expose another...
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Blinding eye disease is strongly associated with heart disease and stroke
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE Patients with a specific form of age-related macular degeneration (AMD), a leading cause of blindness in the United States, are at significant risk for cardiovascular disease and stroke, according to new research from New York Eye and Ear Infirmary of Mount Sinai. This study, published...
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Abnormal heart metabolism may predict future sudden cardiac death
by Johns Hopkins University School of Medicine Credit: Pixabay/CC0 Public Domain Adults with abnormal heart metabolism are up to three times more likely to experience life-threatening arrhythmias (an irregular heart rhythm), and MRI techniques could be used to detect the condition and predict future sudden cardiac death (SCD), according to a small, but rigorous study...
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People of East Asian descent have more vessels reclog after endovascular treatment
by American Heart Association Credit: CC0 Public Domain Among people who received endovascular therapy to mechanically remove a clot in their large brain artery, those who had a rare genetic variant found primarily in people of East Asian descent (Japanese, Chinese and Korean) were more likely to have the vessel reclog during or shortly after...