by Yale University Credit: CC0 Public Domain Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine. Saccular brain aneurysms affect nearly 3% of the human population. If they rupture,...
Category: <span>Prognostic</span>
New biomarkers could predict rheumatoid arthritis susceptibility
by Washington State University Credit: Unsplash/CC0 Public Domain Cells from a cheek swab revealed biomarkers for rheumatoid arthritis that could lead to a way to diagnose and begin treatment before the disease develops, according to a study published in Scientific Reports. In the study, researchers from Washington State University and Arthritis Northwest in Spokane, Washington identified...
New method predicts drug response of cancer patients
by Delft University of Technology Credit: Delft University of Technology Researchers from Delft University of Technology and the Netherlands Cancer Institute (NKI) have developed an algorithm to predict patient response to anti-cancer drugs. This allows us to identify more rapidly if some drugs can have a positive effect on a specific patient, even for complicated...
Several protein biomarkers protect against disease development
by Uppsala University Credit: Unsplash/CC0 Public Domain Inflammatory processes are associated with a large range of human diseases, including rheumatic diseases and allergies. Protein biomarkers are measurable molecules that can have a prognostic value in patients, be used to diagnose disease, or indicate severity of disease. Today, a large number of plasma proteins have been...
Fatty acid length predicts Parkinson’s disease risk
by Will Doss, Northwestern University Long-chain lipids (green) accumulate in the lysosomes (red) of disease cultures (right) but not in healthy cells (left). Credit: Northwestern University Whether or not someone develops Parkinson’s disease may be a game of nanometers. A recent study has demonstrated that chains of fatty acids in the lysosome just one-half nanometer...
Smoke screen: Analysis of saliva from long-term cannabis smokers identifies disruptions in the healthy oral microbiome that may lead to brain disorders
MEDICAL UNIVERSITY OF SOUTH CAROLINA IMAGE: WEI JIANG, M.D., IMMUNOLOGIST AND ASSOCIATE PROFESSOR IN THE DEPARTMENT OF MICROBIOLOGY AND IMMUNOLOGY AT THE MEDICAL UNIVERSITY OF SOUTH CAROLINA. CREDIT: SARAH PACK, MEDICAL UNIVERSITY OF SOUTH CAROLINA More and more states are legalizing marijuana, but little is known about how long-term cannabis use affects the microbes in...
New way to identify early risks of cardiovascular disease
by Karolinska Institutet Credit: Unsplash/CC0 Public Domain The risk of developing cardiovascular disease is strongly associated with the “bad” LDL cholesterol. A large study by scientists at Karolinska Institutet now shows that two proteins that transport cholesterol particles in the blood provide early and reliable risk information. The researchers now advocate introducing new guidelines for detecting...
Elevated heart rate linked to increased risk of dementia
KAROLINSKA INSTITUTET IMAGE: YUME IMAHORI, POSTDOC RESEARCHER AT THE DEPARTMENT OF NEUROBIOLOGY, CARE SCIENCES AND SOCIETY, KAROLINSKA INSTITUTET. CREDIT: STEFAN ZIMMERMAN Having an elevated resting heart rate in old age may be an independent risk factor of dementia, according to a study at Karolinska Institutet in Sweden published in the journal Alzheimer’s & Dementia: The Journal...
Inherited mutation linked to aggressive prostate cancer
Men who inherit mutations in a gene called TP53 have a high risk of developing aggressive prostate cancer, a multicenter research team in the United States has found. The findings were reported in the journal European Urology. Researchers from more than a dozen institutions across the United States collaborated on the study. Dr. Kara N. Maxwell, assistant professor...
New findings on bacteria that increase risk of pancreatic cancer
Bacteria from the digestive system seem to have the potential to cause damage to pancreatic cells, increasing the risk of malignant tumours. Now for the first time, live bacteria from cystic pancreatic lesions that are precursors to pancreatic cancer, have been analysed by researchers at Karolinska Institutet in Sweden. The study, which is published in Gut...