by University of East Anglia Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia Researchers at the University of East Anglia have shown that a prostate cancer urine test can identify men at ‘intermediate risk’ who can safely avoid immediate treatment and benefit from ‘active surveillance’ instead. A new pilot...
Category: <span>Prognostic</span>
EEG HELPS PREDICT IF TREATMENT WILL BENEFIT PEOPLE WITH EPILEPSY
For the study researchers used a new statistical model that is 80% accurate in distinguishing between drug-resistant and drug-responsive generalized epilepsy. “Traditionally, we had few tools available to help us predict whether a patient will do well and remain seizure-free or continue to have seizures despite treatment with medications. “This is difficult for patients to hear, especially...
Liquid biopsies one step closer to entering the clinic to help guide breast cancer treatment
by Institute of Cancer Research Credit: Ahmad Ardity via Pixabay A simple blood test can identify specific genetic mutations in patients’ breast tumors to help guide their treatment and assess how likely patients are to relapse, a study shows. By allowing clinicians to better understand the genetic characteristics of individual breast cancers, the blood test can be used to...
Children with mental health problems at increased risk for mental disorders as adults
by Murdoch Children’s Research Institute Credit: Unsplash/CC0 Public Domain Children with mental health problems were at increased risk of developing a mental disorder as an adult, a new systematic review has found. The research led by the Murdoch Children’s Research Institute (MCRI) and published in Neuroscience and Biobehavioral Reviews, found prevention and early intervention should...
Impaired vision increases risk of depression in midlife women
THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (Oct. 27, 2021)—Midlife women are known to have the highest prevalence of depression compared with all other age groups, and women have higher depression rates than men. A new study suggests that midlife vision impairment is associated with increased odds of future depressive symptoms for midlife women....
Genetic biomarker test predicts recurrence and survival outcomes for men with high-risk prostate cancer
AMERICAN SOCIETY FOR RADIATION ONCOLOGY ARLINGTON, Va., October 25, 2021 — A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy. The study, which examined biopsy samples collected from three large, randomized clinical trials, indicates that physicians potentially can...
Genetic risk test developed to predict alcohol-related cirrhosis of the liver
by Centenary Institute Graphical abstract. Credit: DOI: 10.1016/j.jhep.2021.10.005 An international research group led by the Centenary Institute has developed a world first genetic risk score (GRS) test able to identify patients at high-risk of developing alcohol-related cirrhosis. Cirrhosis (scarring of the liver) is responsible for approximately 300,000 deaths each year world-wide. In their study the researchers...
Gut-brain axis response to inflammation may underlie inflammatory bowel disease
In response to gut inflammation, such as that caused by inflammatory bowel disease (IBD), the vascular barrier in the brain choroid plexus closes, locking down access to the brain, according to a new study. While this gut-brain vascular axis deregulation likely protects the brain from inflammation, the findings suggest it may also result in the...
Short-sleepers are more likely to suffer from irregular and heavy periods
by Kat Kennedy, Sara Nowakowski, The Conversation Credit: Unsplash/CC0 Public Domain Menstruating women who sleep less than six hours a night tend to suffer heavier and irregular periods. That is the conclusion from our new study, which was recently published in the Journal of Sleep Research. We found that those who got less than six hours...
Targeted prostate cancer screening could benefit men with inherited cancer syndrome
by Institute of Cancer Research Credit: Unsplash/CC0 Public Domain Men who inherit an increased risk of cancer through “Lynch syndrome” could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Lynch syndrome raises the risk of several cancer types including—most famously—bowel cancer, and affects 175,000 people in the...