INDIANAPOLIS – Researchers have created novel scoring tools for predicting actual risk of colon cancer and advanced precancerous polyps for patients at average for the disease. The work was led by Thomas F. Imperiale, M.D., Regenstrief Institute and U.S. Department of Veterans Affairs research scientist and Indiana University School of Medicine professor of medicine. The...
Category: <span>Prognostic</span>
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BLACK WOMEN HAVE NEARLY 3X HIGHER TRIPLE NEGATIVE BREAST CANCER
These types of cancer have a poor prognosis. The analysis of nearly 200,000 patients who received mammograms between 2006 and 2015 across three US health systems underscores the importance of understanding the heterogeneity of breast cancer risk factors for women of differing races, ages, and disease subtypes. The study appears in Cancer Medicine. The cohort included...
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Scientists investigate how infection by SARS-CoV-2 can lead to kidney disorders
IMAGE: LOSS OF ACE2 LEADS TO AN IMBALANCE IN SYSTEMS THAT REGULATE ESSENTIAL METABOLIC FUNCTIONS, IMPAIRING BLOOD FILTRATION AND CAUSING KIDNEY INJURIES THAT CAN BECOME PERMANENT CREDIT: HOLLY FISCHER/HOLLY FISCHER/WIKIMEDIA COMMONS HTTPS://COMMONS.WIKIMEDIA.ORG/WIKI/FILE:KIDNEY_CROSS_SECTION.PNG A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of São Paulo (UNIFESP) in Brazil discusses the mechanisms whereby SARS-CoV-2...
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Scientists investigate how infection by SARS-CoV-2 can lead to kidney disorders
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: LOSS OF ACE2 LEADS TO AN IMBALANCE IN SYSTEMS THAT REGULATE ESSENTIAL METABOLIC FUNCTIONS, IMPAIRING BLOOD FILTRATION AND CAUSING KIDNEY INJURIES THAT CAN BECOME PERMANENT CREDIT: HOLLY FISCHER/HOLLY FISCHER/WIKIMEDIA COMMONS HTTPS://COMMONS.WIKIMEDIA.ORG/WIKI/FILE:KIDNEY_CROSS_SECTION.PNG A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of...
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Research bolsters link between diabetes and Alzheimer’s disease
by University of Nevada, Las Vegas Credit: Pixabay/CC0 Public Domain A team of UNLV neuroscientists has strengthened the link between Type II diabetes and Alzheimer’s disease. In a study published in the September issue of the journal Communications Biology, researchers show that chronic hyperglycemia impairs working memory performance and alters fundamental aspects of working memory networks. “Diabetes is a...
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Link between hypercholesterolemia and bladder cancer aggressiveness
by Liu Jia, Chinese Academy of Sciences Credit: Pixabay/CC0 Public Domain Hypercholesterolemia is a metabolic disorder commonly found in people with obesity. It has been reported as a risk factor in the development of the cancers derived from steroid-targeted tissues, such as breast and prostate cancer. However, little is known about the effects of hypercholesterolemia on...
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Blood pressure rising at night linked to doubling risk of death in adults with diabetes
DALLAS, Sept. 27, 2021 — Adults with type 1 or type 2 diabetes whose blood pressure increased at night had more than double the risk of dying compared to those whose blood pressure “dipped” during sleep, according to a 21-year study presented today at the American Heart Association’s Hypertension Scientific Sessions 2021. The meeting is the...
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Time until dementia symptoms appear can be estimated via brain scan
Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person who is likely to develop Alzheimer’s disease but has no cognitive symptoms, will start showing signs of Alzheimer’s dementia. The algorithm, available online in the journal Neurology, uses data from a kind of brain scan known...
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Serum biomarker of fibrosis predicts kidney function decline
High levels of a polyubiquinated form of phosphatase and tensin homolog (PTEN) were associated with an almost four-fold higher risk of a 40% decline in kidney function in a cohort of American Indians with or at high risk of diabetic kidney disease. A recently identified modified form of the protein PTEN has been implicated in...
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New scoring system helps identify kids at risk for post-concussion symptoms
by Ellen Goldbaum, University at Buffalo Problems with vision are among those that UB researchers have identified as an indication that a child or adolescent with a concussion will have delayed recovery. Credit: Douglas Levere Researchers at the University at Buffalo’s Concussion Management Clinic have developed a brief, standardized physical exam for sport-related concussive brain injuries in children...