by The Mount Sinai Hospital Credit: CC0 Public Domain Sets of genes associated with resistance to immunotherapy in patients with metastatic urothelial cancer of the bladder have been identified and validated by researchers at Mount Sinai. In a study published in Clinical Cancer Research, the team uncovered gene signatures representing adaptive immunity and pro-tumorigenic inflammation that were responsible for sensitivity or...
Category: <span>Prognostic</span>
A weak heart makes a suffering brain
Heart problems cause disturbed gene activity in the brain’s memory center, from which cognitive deficits arise. Researchers at the German Center for Neurodegenerative Diseases (DZNE), the University Medical Center Göttingen (UMG) and the German Center for Cardiovascular Research (DZHK) come to this conclusion based on laboratory studies. They consider that they have found a possible...
An amyloid link between Parkinson’s disease and melanoma
by American Chemical Society Immunofluorescence images show that some α-synuclein and Pmel17 are in the same locations in human melanoma cells. Credit: Dexter Dean, Ph.D. On the surface, Parkinson’s disease—a neurodegenerative disorder—and melanoma—a type of skin cancer—do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson’s disease patients...
Study refutes theory that blood type affects COVID risk
by Dennis Thompson, Healthday Reporter A or B, AB or O, it doesn’t matter—your blood type has nothing to do with your risk of contracting severe COVID-19, a new study concludes. Early in the pandemic, some reports suggested people with A-type blood were more susceptible to COVID, while those with O-type blood were less so....
Adults who suffer from gum disease are TWICE as likely to have high blood pressure, study warns
By JOE PINKSTONE FOR MAILONLINE People with severe gum disease are twice as likely to have high blood pressure, according to a new study. A study of 250 people with periodontitis — severe gum disease — found people with the condition are 2.3 times more likely to have a systolic blood pressure higher than 140...
Six pregnancy complications are among red flags for heart disease later in life
AMERICAN HEART ASSOCIATION DALLAS, March 29, 2021 — Six pregnancy-related complications – high blood pressure, gestational diabetes, preterm delivery, small-for-gestational-age delivery, pregnancy loss or placental abruption – increase a woman’s risk for developing cardiovascular disease (CVD) later in life, according to a new scientific statement from the American Heart Association, published today in the Association’s...
Cervical cancer testing tech could replace pap smears, save lives
AMERICAN INSTITUTE OF PHYSICS IMAGE: ARTIFICIAL INTELLIGENCE MONITORING FOR HPV (AIM-HPV) DEVICE FOR POINT-OF-CARE HPV TESTING. CREDIT: ISMAIL DEGANI (CENTER FOR SYSTEMS BIOLOGY, MASSACHUSETTS GENERAL HOSPITAL) WASHINGTON, March 30, 2021 — Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives both in developing nations and parts...
Relationship between psoriasis treatments and cardiovascular risk explained
CACTUS COMMUNICATIONS IMAGE: Various treatment options exist for psoriasis, and they differ in terms of potential effects on a patient’s risk of cardiovascular events. A recent review article in the Chinese Medical Journal can help dermatologists and their patients understand those effects. CREDIT: ESTZER MILLER ON PIXABAY Psoriasis is a chronic disease that causes patients...
Large study identified new genetic link to male infertility
ESTONIAN RESEARCH COUNCIL IMAGE: THE PREVALENCE OF THE Y-CHROMOSOMAL HAPLOGROUP R1A1-M458 CARRYING A FIXED R2/R3 INVERSION. (A) GEOGRAPHICAL DISTRIBUTION OF HAPLOGROUP R1A1-M458 AND ITS SUB-LINEAGES IN EUROPE. PIE CHARTS INDICATE POPULATIONS, WITH THE BLACK SECTOR SHOWING THE PROPORTION OF R1a1-M458 ACCORDING TO UNDERHILL et al., 2015. CREDIT: UNIVERSITY OF TARTU The findings published in eLife show that...
Almost one in seven suffers long COVID, UK study finds
Credit: Pixabay/CC0 Public Domain Nearly one in seven Britons who tested positive for COVID-19 continued to have symptoms for at least 12 weeks, according to a UK study released Thursday. The Office for National Statistics said the study of over 20,000 people who had tested positive from April last year to March this year found...