Category: <span>Prognostic</span>

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Body changes detected up to eight years before inflammatory bowel disease diagnosis
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Body changes detected up to eight years before inflammatory bowel disease diagnosis

by The Francis Crick Institute Credit: CC0 Public Domain Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn’s disease and up to three years before a diagnosis of ulcerative colitis. This means the beginnings of...

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Blood test predicts MS disability worsening up to two years in advance

Reviewed by Danielle Ellis, B.Sc.Nov 6 2023 Multiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability one to two years later, according to a new study spearheaded by researchers at UC San Francisco. The study is the first to quantify the timeframe preceding disability worsening in...

Prediabetes and persistent tobacco use may triple risk of stroke in healthy young adults
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Prediabetes and persistent tobacco use may triple risk of stroke in healthy young adults

by American Heart Association Credit: CC0 Public Domain The combination of persistent tobacco use and prediabetes (higher than normal blood sugar levels that may progress to type 2 diabetes) triples the risk of stroke in young adults who do not have other cardiovascular risk factors, according to a preliminary study presented at the American Heart Association’s...

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Shorter white blood cell telomeres linked to higher dementia risk

Peer-Reviewed Publication SHANGHAI JIAO TONG UNIVERSITY JOURNAL CENTER SHORTER LTL IS ASSOCIATED WITH TOTAL AND REGIONAL BRAIN STRUCTURE AND A HIGHER RISK OF INCIDENT DEMENTIA AND AD, IMPLYING THE POTENTIAL OF TELOMERE LENGTH AS A PREDICTIVE BIOMARKER OF BRAIN HEALTH. CREDIT: ZHI CAO ET AL. Shorter telomeres on the ends of white blood cell chromosomes...

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High metabolism is an early sign of Alzheimer’s disease, finds study

by Karolinska Institutet Credit: CC0 Public Domain An early phase in the process of developing Alzheimer’s disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry. The discovery opens up for new potential methods of early intervention. Alzheimer’s disease is...

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New thesis on prognostication for patients with myelodysplastic syndrome

by Karolinska Institutet Credit: Pixabay/CC0 Public DomainMaria Creignou from the Hematology Unit (HERM) at the Department of Medicine, Huddinge (MedH) is defending her thesis: “Improving prognostication for patients with myelodysplastic syndromes” on 27 October 2023. Her main supervisor is Professor Eva Hellström Lindberg (MedH). What is the main focus of your thesis?My thesis is about a...

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Pupil response may shed light on who responds best to transcranial magnetic stimulation for depression

Two new studies from UCLA Health suggest that the “window to the soul” may give a glimpse into the brain in depression Peer-Reviewed Publication UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES New findings from researchers at UCLA Health suggest that measuring changes in how pupils react to light could help predict recovery from depression...

Metabolite in urine predicts diabetic kidney failure 5–10 years early: Oral therapeutic drug shows promise in mice
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Metabolite in urine predicts diabetic kidney failure 5–10 years early: Oral therapeutic drug shows promise in mice

by University of Texas Health Science Center at San Antonio Credit: Pixabay/CC0 Public DomainUrine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health...

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The long-term course of severe long COVID

CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN Patients who still have health problems three months after a SARS-CoV-2 infection, with symptoms ongoing for at least two months and no other explanation for these issues, are said to have post-COVID syndrome (PCS), also known as “long COVID.” Symptoms vary widely. Many people have problems with breathing, trouble concentrating, or...

Study shows prevalence of hearing loss significantly higher for cancer survivors
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Study shows prevalence of hearing loss significantly higher for cancer survivors

by Elana Gotkine Cancer survivors have a significantly higher prevalence of hearing loss (HL) than the general population, according to a study published online Oct. 5 in JAMA Otolaryngology-Head and Neck Surgery. Qian Wang, M.D., M.P.H., from the University Hospitals Seidman Cancer Center in Cleveland, and colleagues estimated the prevalence of subjective and objective HL...