UArizona College of Medicine — Phoenix study increases understanding of most common bacterial infection in US women UNIVERSITY OF ARIZONA HEALTH SCIENCES PHOENIX – Women with bacterial vaginosis exhibit elevated levels of the pro-inflammatory protein, IL-36y, according to a new collaborative study led by the University of Arizona College of Medicine-Phoenix. CREDIT: IMAGE COURTESY OF...
Category: <span>Proteomics</span>
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Researchers find protein promotes cancer, suppresses anti-tumor immunity
Targeting TBK1 in mice thwarts lung cancer development, frees immune response UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER HOUSTON — Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease. Working...
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A lifeline for leaky lung cells
by Harvard University Leaky lungs are a very common side effect of heart failure, but all currently available drugs do is reduce the amount of fluid in the body, rather than plug the leak itself. A new gene therapy created at the Wyss Institute and Boston Children’s Hospital and tested in human Lung Chips blocks...
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Protein protects the mitochondria and surprisingly rescues neurons from stroke-like damage
by Delthia Ricks , Medical Xpress Credit: CC0 Public Domain A protein newly discovered by scientists in China is aiding in the dramatic reversal of stroke-like damage in laboratory animals and may one day rescue humans from neurological injury, the research team is predicting. Their work is based on a series of breakthrough studies involving mitochondria, bean-shaped...
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Easier Way of Sneaking Antibodies into Cells
For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked to antibodies as a way of shutting down proteins inside cells for decades, but there is still no consistent way to get...
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Lab leads effort to model proteins tied to cancer
This news or article is intended for readers with certain scientific or professional knowledge in the field. Computational scientists, biophysicists and statisticians from Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL) are leading a massive multi-institutional collaboration that has developed a machine learning-based simulation for next-generation supercomputers capable of modeling protein interactions...
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1 PROTEIN MAY SHIELD WOMEN FROM HERPES ‘NEUROINVASION’
A pro-inflammatory protein could play an important part in improving current and future therapeutics for the herpes virus, according to new research. Researchers investigated whether the protein IL-36g is an essential component of the immune response to a herpes infection, or if other mechanisms can compensate for a lack of it. Cytokines, proteins essential to...
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Scientists discover the implication of a new protein involved in liver cancer
The finding has a clear clinical relevance, since it will facilitate patient selection to offer a more specific therapy IDIBELL-BELLVITGE BIOMEDICAL RESEARCH INSTITUTE Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have just described for the first time the crucial involvement of a cell membrane protein in the development and progression of liver cancer, according...
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New insights could help block the path of cancer ‘super-highways’
by The Francis Crick Institute A key mechanism controlling tissue structure, which could help identify drugs that make it harder for cancer cells to spread, has been identified by researchers at the Francis Crick Institute. The two studies, published in Nature Materials and PLOS Computational Biology, explain the mechanism that causes changes in the structure...
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Scientists identify new potential treatment pathway for cardiovascular disease
by University of Sheffield Scientists from the University of Sheffield have identified a new potential treatment pathway for cardiovascular disease. Their research has shown for the first time that a protein expressed in a subset of immune cells contributes towards the build-up of fatty deposits in arteries, which leads to cardiovascular disease. These fatty deposits...