Category: <span>Proteomics</span>

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Liver damage from drinking may one day be REVERSIBLE: Scientists are developing a drug to undo tissue scarring in lung and liver disease

Scar tissue forms in the place of healthy tissue in organs  This process is called cirrhosis in the liver and fibrosis in the lungs  Its a hallmark of liver and lung diseases triggered by excessive drinking and smoking  This damage is currently irreversible, incurable and can prove fatal  But Mayo Clinic researchers discovered they can block two proteins to tell scar tissue precursors to do the opposite, removing and breaking down...

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Brown and white body fat speak different languages

by University of Copenhagen Many people might not realize that they have different types of body fat. Most of it is white fat that sits on your stomach, hips and thighs, for example. White fat is an energy storage that our body can use when food is scarce. White fat also produces and receives signals...

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By targeting flu-enabling protein, antibody may protect against wide-ranging strains

The findings could lead to a universal flu vaccine and more effective emergency treatments SCRIPPS RESEARCH INSTITUTE LA JOLLA, CA – A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or...

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Protein in blood protects against neuronal damage after brain hemorrhage

UNIVERSITY OF ZURICH Patients who survive a cerebral hemorrhage may suffer delayed severe brain damage caused by free hemoglobin, which comes from red blood cells and damages neurons. Researchers at the University of Zurich and the UniversityHospital Zurich have now discovered a protective protein in the body called haptoglobin, which prevents this effect.  Bleeding in the narrow space between the inner and middle meninges...

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Whitehead Institute team resolves structure of master growth regulator

Posted Yesterday This news or article is intended for readers with certain scientific or professional knowledge in the field. A team of Whitehead Institute scientists has for the first time revealed the molecular structure of a critical growth regulator bound to its partner proteins, creating a fine-grained view of how they interact to sense nutrient...

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Otago scientists’ discovery leads to greater understanding of Alzheimer’s disease

UNIVERSITY OF OTAGO Otago scientists have made an important discovery in understanding the role a particular protein plays to impair memory in Alzheimer’s disease, which could lead to more effective treatment in future. Professor Cliff Abraham and Dr Anurag Singh from the Department of Psychology have identified that a protein in the brain – tumor...

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Newly discovered protein is the permit to the powerhouse of cells

Medical University of South Carolina researchers report in Science Advances that they have discovered a protein, P17/PERMIT, that is key to recycling aging mitochondria and could be a connection between age-related diseases such as cancer and Alzheimer’s MEDICAL UNIVERSITY OF SOUTH CAROLINA Aging, and the mechanics behind it, remains one of the most closely guarded...

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Scientists uncover the process behind protein mutations that impact gut health

Study examines why a protein mutation that causes inflammatory bowel diseases is dysfunctional ST. MICHAEL’S HOSPITAL A new study led by researchers at St. Michael’s Hospital and the Princess Margaret Cancer Centre in Canada and Zhejiang University School of Medicine in China has uncovered why a protein mutation that causes inflammatory bowel diseases is dysfunctional. Published today...

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New universe of miniproteins is upending cell biology and genetics

By Mitch LeslieOct. 17, 2019 , 2:00 PM Mice put human runners to shame. Despite taking puny strides, the rodents can log 10 kilometers or more per night on an exercise wheel. But the mice that muscle biologist Eric Olson of the University of Texas Southwestern Medical Center in Dallas and colleagues unveiled in 2015...