UNIVERSITY OF ROCHESTER MEDICAL CENTER IMAGE: STUDY IN SCIENCE SHOWS HOW A CAS PROTEIN PARTNERS WITH A UNIQUE MEMBRANE PROTEIN TO STOP VIRAL INFECTION IN BACTERIA. CREDIT: UNIVERSITY OF ROCHESTER MEDICAL CENTER CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that...
Peer-Reviewed Publication STANFORD UNIVERSITY Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer’s, Parkinson’s, and Huntington’s diseases. Cells work constantly to eliminate misfolded proteins, but these clearance mechanisms are still poorly understood. In a new study published April 20 in Nature Cell Biology, researchers at Stanford University discovered...
BY ELISE OVERGAARD Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer’s, Parkinson’s, and Huntington’s diseases. Cells work constantly to eliminate misfolded proteins, but these clearance mechanisms are still poorly understood. In a new study published April 20 in Nature Cell Biology, researchers at Stanford University discovered a previously unknown...
by Spanish National Research Council Credit: Pixabay/CC0 Public Domain A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington’s disease, a severe neurodegenerative pathology characterized by the progressive disorder of movement and cognitive function. This research, published in the journal Nature...
by Wiley Credit: Pixabay/CC0 Public Domain In research published in The FASEB Journal, scientists have discovered that a molecule called Yes-associated protein (YAP) plays a key role in the development of liver scarring, or fibrosis, by influencing the behavior of premature cells called liver progenitor cells. By manipulating YAP expression in these cells, the investigators were able to improve...
UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE/UW MEDICINE IMAGE: MICROSCOPIC 2D AND 3D IMAGES OF UNIVERSITY OF WASHINGTON HUSKY LOGOS AND A DOG WERE MADE WITH A NEW CHEMISTRY TECHNIQUE, SPYLIGATION, THAT PRECISELY CONTROLS WHEN AND WHERE PROTEINS TURN ON. CREDIT: COLE DEFOREST RESEARCH GROUP Scientists can now use light to activate protein functions both inside and outside...
By Jason Mast April 13, 2023 Reprints Hibernating bears in Sweden have become enticing research subjects. COURTESY OLE FRØBERT Like many cardiologists, Manuela Thienel spends most days in the chlorinated, temperature-controlled halls of a large hospital. But one week in February 2019, her work brought her to a snowy Swedish forest, where she stood shuddering...
UNIVERSITY OF HOUSTON IMAGE: ASHOK KUMAR, ELSE AND PHILIP HARGROVE ENDOWED PROFESSOR OF PHARMACY AND CHAIR OF THE DEPARTMENT OF PHARMACOLOGICAL AND PHARMACEUTICAL SCIENCES IN THE UH COLLEGE OF PHARMACY, IS EXAMINING MUSCLE WASTING IN HOPES TO DEVELOP A PREVENTIVE MEDICINE. CREDIT: UNIVERSITY OF HOUSTON Skeletal muscle atrophy, or wasting, is a devastating and often...
Scientists are looking into the causes of gout. Design by MNT; Photography by Hulton Archive/Getty Images & Solskin/Getty Images An international research team identified a novel molecular pathway believed to cause gout and its progression to erosion of joint tissue. Researchers believe lubricin, a protein found in joint fluid, may serve as a novel therapeutic...
by University of Wyoming University of Wyoming student Maxwell Packebush works with Silvia Sanchez-Martinez, a senior research scientist, to purify one of the tardigrade proteins used in a study showing that the proteins can be used to stabilize an important pharmaceutical for people with hemophilia and other conditions without the need for refrigeration. Credit: Thomas Boothby...
