DECEMBER 1ST, 2022 CONN HASTINGS GENETICS, MEDICINE Scientists at Hong Kong University of Science and Technology came up with a technique to increase the efficiency and potentially the efficacy of mRNA therapeutics. mRNA molecules have what is called a poly-A tail, which is basically a string of adenine nucleotides at one end. These researchers discovered...
OHIO STATE UNIVERSITY COLUMBUS, Ohio – Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into “roads to nowhere,” redirecting the proteins away from other jobs that are key to proper cell function, a new study has found. The affected proteins are known as...
UNIVERSITY OF CAMBRIDGE Water – which makes up the majority of every cell in the body – plays a key role in how proteins, including those associated with Parkinson’s disease, fold, misfold, or clump together, according to a new study. When attempting to discover potential treatments for protein misfolding diseases, researchers have primarily focused on...
by University of Edinburgh Credit: Pixabay/CC0 Public Domain Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease. Levels of a key protein—called TLR2—in tumors was found to predict a patient’s survival after being diagnosed with lung cancer, their...
RCSI Research by RCSI University of Medicine and Health Sciences has discovered a new role for the blood clotting protein, von Willebrand Factor (VWF), that could lead to the development of new treatments for patients with inflammatory and blood clotting disorders. Published in Nature Communications, the research finds that VWF plays an important role in regulating...
UNIVERSITAT AUTONOMA DE BARCELONA Endometrial cancer is the most common type of gynecological cancer and is the fourth most common type of tumor in women in developed countries. Although it has a good prognosis if detected early, advanced and aggressive cases have a high mortality rate and are often resistant to standard chemotherapy treatments. Now,...
THE HOSPITAL FOR SICK CHILDREN In a ground-breaking new study, scientists have uncovered the mechanics of the blood-tumour barrier, one of the most significant obstacles to improving treatment efficacy and preventing the return of cancerous cells. The research team, led by Dr. Xi Huang, a Senior Scientist in Developmental & Stem Cell Biology program at The Hospital for Sick...
JOHNS HOPKINS MEDICINE In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people. The protein, a cation channel known as TRPM7, is found in carotid bodies, tiny sensory...
SCRIPPS RESEARCH INSTITUTE IMAGE: HIGH-RESOLUTION IMAGES SHOWING THE FULL LENGTH OF E1E2 IN COMPLEX WITH THREE BROADLY NEUTRALIZING ANTIBODIES, FROM TWO ANGLES. CREDIT: SCRIPPS RESEARCH LA JOLLA, CA—A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud...
By Michael Irving October 02, 2022 A new study could recontextualize metastasis in cancer Deposit photos Cancer’s ability to spread through the body is one of its most devastating tricks. Scientists at Cambridge have now identified a protein that plays a key role in metastasis, which not only hints at a new potential treatment but...
