by University of Otago Targeted methylation sequencing in order to validate the 850K methylation data. Credit: Cancer Letters (2025). DOI: 10.1016/j.canlet.2025.217638 A major step forward has been made in predicting how well melanoma patients would respond to treatment, thanks to world-leading University of Otago—Ōtākou Whakaihu Waka research. More than 7,000 melanomas are diagnosed each year in Aotearoa New...
Category: <span>Research Updates</span>
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Full recovery after a child’s concussion may take longer than previously thought
by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain University of Montreal-led research has found that children who sustain concussion may need three months or longer to be considered optimally recovered across physical, cognitive, socioemotional, and resilience domains. Concussion affects millions of children annually, leading to physical, cognitive, sleep, and emotional symptoms which can...
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Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models
by Joseph Caputo, Tufts University The X-ray structure of CspZ-YA and the mutagenesis of amino acid residues in CspZ-YA by structure-based vaccine design. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-58182-x Meeting the unmet need for a vaccine is the top priority for researchers studying Lyme disease, which infects about 476,000 people in the U.S. each year and can come...
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Is AI in medicine playing fair? Researchers stress-test generative models, urging safeguards
by The Mount Sinai Hospital A new study raises concerns regarding responsible AI in health care. Researchers at the Icahn School of Medicine at Mount Sinai found that AI models can make different treatment recommendations for the same medical condition based on a patient’s socioeconomic and demographic background. This highlights the need for safeguards to ensure...
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New findings on T cell exhaustion: The body prepares early for mild to severe disease
by Anja Lapac, Technical University Munich Cells similar to memory precursor T cells and to exhausted precursors exist early in acute infection. Credit: Nature (2025). DOI: 10.1038/s41586-024-08451-4 Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team from the Technical University of Munich (TUM)...
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Stroke breakthrough takes aim at the gut
By Bronwyn Thompson April 06, 2025 Scientists are looking at the gut-brain connection and stroke rehabilitation Depositphotos View 2 Images What does gut fermentation and stroke-induced brain inflammation have in common? Potentially a lot, according to new research looking into how the microbiome directly influences brain inflammation. It could make recovery faster, reduce cognitive impairment and...
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No Bones About It: New Details About Skeletal Cell Aging Revealed
April 04, 2025 It’s no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones. Scientists and researchers around the globe are investigating a series of mysteries about what happens...
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Scientists reveal new toxin that damages the gut
by La Trobe University Epithelial cells that have been damaged by the EspC toxin. Credit: La Trobe University Scientists at La Trobe University have discovered how a diarrhea-causing strain of bacteria uses “molecular scissors” to cut open and destroy gut cells, leading to severe illness and sometimes death. Published in Gut Microbes, the research reveals for the...
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Artificial sweetener shows surprising power to overcome antibiotic resistance
by Hayley Jarvis, Brunel University Impact of saccharin on cellular growth and morphology. Credit: EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00219-1 Saccharin, the artificial sweetener used in diet foods like yogurts and sugar-free drinks, can kill multidrug-resistant bacteria—including one of the world’s most dangerous pathogens. “Antibiotic resistance is one of the major threats to modern medicine,” said Professor Ronan...
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New hope for millions: Researchers find key to treating painful dry mouth disorder
by Chinese Academy of Sciences A schematic diagram illustrates a proposed mechanism of interferon-γ (IFN-γ)-induced downregulation of tricellulin in salivary epithelial cells. The schematic diagram is designed by Figdraw. Credit: International Journal of Oral Science (2025). DOI: 10.1038/s41368-025-00349-9 Sjögren’s syndrome is a chronic autoimmune disorder that affects millions worldwide, especially women, causing unrelenting dryness of the mouth...