DECEMBER 30TH, 2024POSTED BY U. MICHIGAN (Credit: Getty Images) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY UNIVERSITY OF MICHIGAN A new study shows that when people’s sleep cycles aren’t aligned with their internal clocks, or circadian rhythms, it can have drastic effects on their moods. Conversely, however,...
Category: <span>Research Updates</span>
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Advances in gene and cellular therapeutic approaches for Huntington’s disease
Peer-Reviewed Publication Higher Education Press image: Highlighting current and emerging gene and cell therapy strategies for Huntington’s Disease is crucial due to the disorder’s complexities and devastating impact. Looking ahead, a synergistic approach that integrates various cell types, genetic correction, and enhancement of the cerebral microenvironment offers significant potential for advancing therapeutic efficacy for Huntington’s...
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Targeting tristetraprolin in basophils: A breakthrough in allergic inflammation treatment
Exploring the role of Tristetraprolin in basophil-mediated immune responses and its therapeutic potentialPeer-Reviewed Publication Institute of Science Tokyo image: TTP regulates inflammatory responses in basophils and isa promising therapeutic target for allergies.view more Credit: Science Tokyo Inflammation is a crucial part of the body’s defense mechanism, playing a key role in fighting infections and repairing tissue...
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New insights into protein roles in Duchenne muscular dystrophy
by CU Anschutz Medical Campus Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.108002 A new study has shed light on the complex interactions between dystrophin, a protein critical to muscle stability, and its partner protein, dystrobrevin, offering new pathways for understanding and treating Duchenne Muscular Dystrophy (DMD). Published in the December issue of the Journal of Biological Chemistry, researchers characterize...
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Mitochondrial DNA plays an underappreciated role in leukemia development
by St. Jude Children’s Research Hospital Xiujie Li-Harms, Ph.D. (pictured), director of laboratory operations in the lab of Mondira Kundu, MD, Ph.D., St. Jude Department of Cell & Molecular Biology, and first author on research published in Science Advances demonstrating the impact of mitochondrial DNA mutational burden on leukemogenesis, revealing a mutational “sweet spot” where leukemia development was...
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Drug development’s quantum leap
By Alison Snyder Illustration: Maura Losch/Axios Quantum computing and biotech companies are testing whether next-generation computing technology could help them develop better drugs and cut the time and cost of finding new ones.Why it matters: Making drugs faster and cheaper with quantum computers could solve one of pharma’s most vexing problems and simplify a process that...
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Key players in brain aging: New research identifies age-related damage on a cellular level
by Allen Institute for Brain Science Non-neuronal brain cells called tanycytes illuminated and color coded according to their depth in the hypothalamus brain of a mouse. They are one of the cell types in the mouse brain that show a large number of gene transcripts changing with age. Credit: Allen Institute Scientists at the Allen Institute...
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Genetic bias in cells: Why some genes favor mom or dad, and what it means for disease outcomes
by Alan Dove, Columbia University Irving Medical Center Ex vivo clonally expanded primary T cells used for detection of aRMAE. Credit: Nature (2025). DOI: 10.1038/s41586-024-08346-4 New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. ADVERTISING Every biology student learns that...
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Restricting calories may extend life. Can this molecule do it without the hunger pangs?
Lithocholic acid replicates antiaging effects of food restriction in mice, other animals DUKA82/ISTOCK SHARE: It’s a dismaying thought during a holiday season full of cookies and big meals, but severely restricting calories consumed is one of the best supported strategies for a healthier, longer life. Slicing food consumption stretches the lives of animals in lab...
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SCIENCE & TECHNOLOGY NEWS
Life-changing cream to treat skin cancer moves closer to reality Posted Today A topical cream to help prevent and treat skin cancers in organ transplant patients is a step closer to development. Skin – illustrative photo. Image credit: Pixabay (Free Pixabay license) The world-first treatment, currently being developed by University of Queensland researchers, has received $344,000 in funding...