They might not make you beautiful, but research suggests exosomes might help us diagnose and treat diseases. By November 1, 2024 GETTY IMAGES This article first appeared in The Checkup, MIT Technology Review’s weekly biotech newsletter. To receive it in your inbox every Thursday, Over the past month or so, I’ve been working on a story about exosomes....
Category: <span>Research Updates</span>
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Immunocompromised may not produce enough protective antibodies against RSV after vaccination, says new study
by Johns Hopkins University School of Medicine Scanning electron micrograph of human respiratory syncytial virus (RSV) virions (colorized blue) and tagged with antibodies (colorized yellow) against the virus’ fusion protein — the target of RSV vaccines. Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health Johns Hopkins Medicine researchers have shown that people...
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New technology ‘sees’ how cholesterol causes heart attacks
by Michael Scaturro Credit: Pixabay/CC0 Public Domain The U.S. government’s premier research body has made an important discovery that could help create new drugs to lower “bad” cholesterol, and hopefully prevent heart attacks and stroke. But the interesting part of that story isn’t just the discovery itself, but the technology responsible for it: a relatively...
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Axolotl Offers Promise in Unlocking the Secrets of Skin Regeneration
Doug Brunk December 30, 2024 012 Added to Email Alert For over 200 years, researchers have been captivated by axolotl salamanders (Ambystoma mexicanum) and their remarkable regenerative abilities, seeking to uncover secrets that could revolutionize regenerative medicine, including the scarless healing of wounds. “The axolotl salamander is the most studied animal ever in science for...
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Scientists design nanoparticle drug delivery system for levodopa
System improves motor function in Parkinson’s mice by Lindsey Shapiro, PhD | December 30, 2024 Scientists have developed a nanoparticle drug delivery system designed to enhance brain delivery of levodopa, the mainstay treatment for Parkinson’s disease, while also lowering a type of cellular damage called oxidative stress that’s implicated in the neurodegenerative condition. Advertisement The system was able to improve...
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Preclinical study finds surges in estrogen promote binge drinking in females
Peer-Reviewed Publication Weill Cornell Medicine The hormone estrogen regulates binge drinking in females, causing them to “pregame” – consume large quantities of alcohol in the first 30 minutes after it’s offered, according to a preclinical study led by scientists at Weill Cornell Medicine. The study establishes–for what is thought to be the first time–that circulating...
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New Technique Maps Hundreds of Proteins Simultaneously within Cell Nuclei
Posted Today Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei simultaneously. The method, called ChIP–DIP (Chromatin ImmunoPrecipitation Done In Parallel), is a versatile tool for understanding the inner workings of the nucleus in different contexts, such as disease or development. A schematic describing the ChIP-DIP process. Image...
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Newly discovered mechanism reveals NAD’s role in aging and disease
by University of Bergen Proposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+ fluctuations. Credit: Nature Metabolism (2024). DOI: 10.1038/s42255-024-01174-w UiB researchers are behind a new discovery that tells us how associated neurodegenerative diseases might develop. At the center of this discovery stands a molecule called NAD, or nicotinamide adenine dinucleotide. The results have been published in Nature...
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Recombinant Pertussis Booster Offers Lasting Immunity
Edited by Shreyasi Asthana December 23, 2024 90 TOPLINE: A booster dose of recombinant pertussis vaccines provides sustained immunity in adolescents and young adults even after 5 years, with pertussis toxin (PT)–neutralizing antibody levels remaining 2.5- to 3-fold higher than prevaccination levels. METHODOLOGY: TAKEAWAY: IN PRACTICE: “The 5-year persistence of neutralizing anti-PT antibodies at levels...
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AI spots heart conditions before sufferers have symptoms
Artificial intelligence has been trained to identify those at risk of developing atrial fibrillationTelegraph Reporters Related Topics 28 December 2024 7:47am GMT 28Gift this article free Artificial intelligence is being used to find people with heart conditions before they even have symptoms. In an ongoing trial, a ground-breaking tool scours GP records for “red flags” which...