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Bidirectional association found between rheumatoid arthritis, COPD

by Elana Gotkine There is a bidirectional association between rheumatoid arthritis (RA) and chronic obstructive pulmonary disease (COPD), according to a review published online Dec. 1 in Frontiers in Immunology. Meijiao Wang, from the Zhejiang Chinese Medical University in Hangzhou, and colleagues examined the bidirectional association between RA and COPD in a systematic review of the...

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Breakthrough treatment flips cancer cells back into normal cells

By Michael Franco December 26, 2024 This generative image shows the concept the researchers proved of turning a cancerous cell back into a healthy cell View 1 Images Working with a line of colon cancer cells, Korean researchers figured out a way to throw a few genetic switches to cause the cells to revert back to...

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Stem cells ‘instructed’ to form specific tissues and organs

By Paul McClure December 26, 2024 Researchers have developed a way of guiding stem cells’ development Depositphotos View 1 Images Researchers have created a way to guide and control the development of stem cells into specific tissues and organs, opening the door to developing a means of one day tackling complex diseases like diabetes and Parkinson’s...

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Study reveals macrophages’ misunderstood role in lung fibrosis

by National Jewish Health Credit: Pixabay/CC0 Public Domain Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as “pro-fibrotic” are insufficient to cause fibrosis on their own, opening the door to research that can help advance the...

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Lupus Nephritis Biomarkers ‘Robustly’ Predict Clinical Response, Long-Term Kidney Damage

Tara Haelle December 09, 2024 132 Added to Email Alert WASHINGTON — An investigational 12-protein panel of urinary biomarkers predicted histologically active lupus nephritis (LN) with 86% accuracy, according to research presented at the American College of Rheumatology (ACR) 2024 Annual Meeting. The noninvasive biomarker panel “robustly predicts meaningful and actionable histological findings” in patients with...

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Plant-Based Diet Improves Uric Acid Levels, Gout Symptoms

Jim Kling November 25, 2024 2532 A Mediterranean-inspired plant-based diet improved self-reported measures of gout as well as uric acid levels, a pilot study has found.  There hasn’t been a lot of research on diet in gout, according to Anna Kretova, RD, who presented the study at the annual research symposium of the Gout Hyperuricemia and...

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The Guide to Supplements for Rheumatologic Diseases

Julie Stewart November 04, 2024 5194 Added to Email Alert Many people with rheumatologic diseases try supplements for symptom relief. Here’s what you need to know about some common picks. Dietary supplements were a $159 billion business in the United States last year, and many people with rheumatologic diseases are buying in. Research suggests more than 6 in...

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Management of Children and Adolescents With Long COVID

Ute Eppinger December 23, 2024 570 Added to Email Alert Current management of children and adolescents with long COVID was the focus of various presentations at the 3rd Long COVID Congress in Berlin in November. The congress aimed to facilitate in-depth discussions on recent research projects, diagnostic procedures, and therapeutic approaches to enhance care for long COVID...

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Six Substudies From the Semaglutide Trials: Identifying Mechanisms of Benefit and Whom to Treat

Identifying Mechanisms of Benefit and Whom to Treat Neha J. Pagidipati, MD, MPHDisclosures J Am Coll Cardiol. 2024;84(17)  11 Added to Email Alerts Several trials have documented the cardiovascular (CV) benefits of the glucagon-like peptide-1 receptor agonist (GLP-1 RA) semaglutide, including the SELECT (Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity), STEP-HFpEF (Effect...

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Chatbots Fail Standard Cognitive Test

— Large language models show susceptibility to cognitive impairment by Judy George, Deputy Managing Editor, MedPage TodayDecember 18, 2024 article President-elect Donald Trump may have once scored a perfect 30/30opens in a new tab or window on the Montreal Cognitive Assessment (MoCA), but artificial intelligence (AI) chatbots didn’t perform nearly as well. On the well-known cognitive screen, most chatbots — also...