By Hugo Francisco de SouzaReviewed by Susha Cheriyedath, M.Sc.Dec 22 2024 New study identifies insulin ‘chain-splitting’ during bloodstream transit as a game-changer in understanding and treating diabetes and insulin resistance. Study: Chain splitting of insulin: an underlying mechanism of insulin resistance? Image Credit: Nastasiiaa / Shutterstock In a recent study published in the journal NPJ Metabolic Health and Disease, researchers hypothesize that...
Category: <span>Research Updates</span>
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Development of a global innovative drug in eye drop form for treating dry age-related macular degeneration
Development of an eye drop treatment for dry AMD enhances patient convenience.Peer-Reviewed Publication National Research Council of Science & Technology image: Schematic representation of the construction and screening of a large-scale peptide library targeting TLR signaling proteins, followed by efficacy validation in cellular and animal models.view more Credit: Korea Institute of Science and Technology Age-related macular...
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Study Finds Association Between Statins and Glaucoma
Richard Mark Kirkner December 18, 2024 7105 Adults with high cholesterol taking statins may have a significantly higher risk of developing glaucoma than those not taking the cholesterol-lowering drugs, an observational study of a large research database found. The study, published in Ophthalmology Glaucoma, analyzed electronic health records of 79,742 adults with hyperlipidemia in the All of Us Research...
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A New Weight Loss Drug With No Side Effects? Yes…So Far
Christina Szalinski For people with obesity or type 2 diabetes, glucagon-like peptide 1 (GLP-1) agonists (including Mounjaro, Wegovy, and Ozempic) have been labeled miracle drugs. But they aren’t miraculous for everyone. Research indicates a significant portion of people discontinue using them within a year. The main problems with GLP-1 agonists are that they are expensive and have...
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Is Oral XEN-D0501 the Next Obesity Drug Hype?
Manuela Callari XEN-D0501, a transient receptor potential vanilloid 1 (TRPV1) antagonist, is gaining attention for its potential as an oral tablet to treat type 2 diabetes, obesity, and cardiovascular diseases. Dorte X. Gram, PhD, founder of Pila Pharma, a Swedish pharmaceutical company investigating XEN-D0501, first noticed the connection more than 20 years ago as a researcher at...
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New study reveals how brain stimulation improves cognition, decision-making in mental health disorders
by Alex Smith, University of Minnesota Medical School Set-shift behavioral results and further outcomes of stimulation. (A) Probability of error based on the current variant of the Side rule (left/right nose poke port). There was no significant difference between the two rules (β = -0.006, p = 0.15), demonstrating that as a group, rats did not...
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Research suggests coffee may protect against cognitive decline in people with atrial fibrillation
by American Heart Association Credit: Pixabay/CC0 Public Domain Drinking multiple cups of coffee a day may help prevent cognitive decline in people with atrial fibrillation (AFib or AF), according to new research published in the Journal of the American Heart Association. “Many myths are around, but our study found no reason to discourage or forbid a patient with AFib...
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Light-induced gene therapy disables cancer cells’ energy center
Posted Today Researchers are shining a light on cancer cells’ energy centers – literally – to damage these power sources and trigger widespread cancer cell death. The study focused on disrupting the inner membrane of mitochondria, the primary producers of energy that fuels cell functions. Mitochondria are depicted in yellow in the image above of an osteocarcinoma cell....
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How a newly examined gut microbe drives the gut-lung axis
by Betty Zou, University of Toronto The protozoan Tritrichomonas musculis as seen under a scanning electron microscope. Credit: Kyle Burrows/University of Toronto A team led by University of Toronto researchers has discovered a new communication pathway between the gut and lung. Their findings highlight how a little-known member of the gut microbiome reshapes the lung immune environment to...
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OVERACTIVE CELLS LINKED WITH TYPE 2 DIABETES
DECEMBER 19TH, 2024POSTED BY ROCHITA GHOSH-U. MISSOURI (Credit: Getty Images) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY UNIVERSITY OF MISSOURI Researchers are studying potential therapies to target specific cells linked to the development of disorders like high blood pressure and type 2 diabetes. Their newly released study...