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Researchers discuss the design of 3D-printed microneedles for medical treatments

by Columbia University Credit: Columbia University What does it take to design a new needle for medical use? When the needle needs to be much thinner and sharper than any commercially existing needle and designed to deliver treatments to a previously inaccessible tissue, the answer is years of collaboration between a close-knit team of physicians and...

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Stanford Scientists Rewrite the Ketosis Rulebook: Metabolites That Suppress Hunger and Promote Weight Loss – diet & nutrition

By Stanford UniversityDecember 20, 2024No Comments7 Mins Read FacebookTwitterPinterestTelegram Share Researchers have identified a novel metabolic pathway in ketosis, revealing that “keto” metabolites play a complex role in metabolism and brain energy regulation, potentially rewriting our knowledge of the ketogenic diet’s effects. A Stanford-led team discovered a new ketosis pathway involving BHB-amino acids, shedding light on...

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Major clinical trial suggests vagus nerve stimulation relieves severe depression

by Tamara Schneider, Washington University in St. Louis Stacked bars of partial response, response, and remission rates determined by A) MADRS, B) QIDS-C, C) QIDS-SR, and D) CGI-I at monthly intervals beginning 3 months after baseline in imputed data. Credit: Brain Stimulation (2024). DOI: 10.1016/j.brs.2024.12.1191 People with severe, treatment-resistant depression who received a nerve-stimulating therapy showed significant improvement...

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Scientists Finally Crack 60-Year Mystery Behind Diabetes ‘Wonder Drug’ Metformin

For over 60 years, scientists have been baffled by how metformin, the trusted diabetes drug, works at the cellular level. A new study from Northwestern Medicine uncovers a surprising mechanism tied to the cell’s mitochondria, shedding light on its role in lowering blood sugar and even slowing cancer growth. Arezki Amiri Published on December 20,...

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Surprise Hair Loss Breakthrough: A Sugar Gel Triggers Robust Regrowth

Health20 December 2024 ByCarly Cassella (Kindel Media/Pexels) Earlier this year, scientists stumbled upon a potential new treatment for hereditary-patterned baldness, the most common cause of hair loss in both men and women worldwide. It all started with research on a sugar that naturally occurs in the body and helps form DNA: the ‘deoxyribose’ part of deoxyribonucleic acid. While studying...

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Tiny antennas on cells offer new ALS insights

Peer-Reviewed Publication Vlaams Instituut voor Biotechnologie image:  Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutationview more  Credit: VIB Leuven, 20 December 2024- Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects motor neurons. The average life span after diagnosis of this incurable disease is two to five years. In the relentless...

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Chinese Medical Journal review provides insights into respiratory syncytial virus

Researchers explored the virology and prevention strategies of respiratory syncytial virus, emphasizing the need for effective vaccinesPeer-Reviewed Publication Chinese Medical Journals Publishing House Co., Ltd. image:  Structure of RSV, showing its RNA and protein components that enable cell attachment and invasion. The virus impacts multiple body systems, including the respiratory, cardiovascular, and digestive systems, causing...

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First successful clinical trial of VU319 brings Alzheimer’s treatment one step closer

by Vanderbilt University Credit: ACS Chemical Neuroscience (2024). DOI: 10.1021/acschemneuro.4c00769 Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s...

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New blood test could help identify patients at risk for cognitive impairment

 Reviewed University of California – Los Angeles Health SciencesDec 19 2024 To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate “downstream” biological markers – those at the end of a cascade of events. But a multicenter study led...

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New Trend: Protein Shots for Appetite Control For Even Better Effect of Weight-Loss Medications

Posted Yesterday In a move to capitalize on the surging demand for weight-loss solutions, Nestlé has introduced a novel protein shot designed to help users manage their appetite. With this new product, the Swiss food giant aims at a new category of consumer health products associated with hunger control. Two protein bars – illustrative photo. Image credit: Aleksander...