Peer-Reviewed Publication ELSP The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance. In order to propagate malignancy, circRNAs shuttle through the blood circulation as cell-free molecules or in exosomes, small vesicles where they are transported to various cells. Published in ExRNA, the...
Category: <span>Research Updates</span>
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Aging changes some brain cells more than others
By Paul McClure January 02, 2025 Certain brain cells respond to aging differently than others DALL-E View 3 Images View gallery – 3 images Detailed mapping of 1.2 million brain cells has revealed that not all cell types age in the same way and that some – found in a specific ‘hot spot’ – are more...
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Scientists Discover Common Virus Could Be Causing a Type of Alzheimer’s
Health06 January 2025 ByJess Cockerill CMV-infected human placental cell. (Nephron/CC BY-SA 3.0/Wikimedia Commons) Researchers have discovered a link between a chronic gut infection caused by a common virus and the development of Alzheimer’s disease in some people. Most people encounter cytomegalovirus (CMV) during childhood, and after the initial infection the virus remains in the body for life, usually dormant. By the age of...
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Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
By Helmholtz Zentrum MünchenJanuary 6, 20251 Comment5 Mins Read FacebookTwitterPinterestTelegram Share A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein. Credit: SciTechDaily.com Researchers have discovered that...
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GLP-1s May Cut Risk for Late-Onset Epilepsy
Pauline Anderson December 17, 2024 287 LOS ANGELES — Newer glucose-lowering drugs reduce the risk for late-onset seizures and epilepsy by 24%, with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) cutting the risk by 33%, according to a new meta-analysis. These results are “amazing” considering there are currently no drugs that actually prevent epilepsy, lead...
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How a simple amino acid could shape immune response
by University of Oxford Credit: Zhi Yi Wong A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response. Germinal center (GC) B cells are responsible for producing antibodies. The cells have some of the highest proliferation rates of all...
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Study shows ‘good’ cholesterol may protect against brain atrophy, dementia
by UT Southwestern Medical Center Credit: Pixabay/CC0 Public Domain High-density lipoprotein (HDL), or “good” cholesterol, may play a vital role in conserving healthy brain matter in middle-aged adults, UT Southwestern Medical Center researchers report. The findings, published in the Journal of Clinical Medicine, could give doctors and patients more insight into factors that affect cognitive health in aging...
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First of its kind gene therapy model offers hope for X-linked sideroblastic anemia treatment
by Children’s Hospital of Philadelphia Credit: Pixabay/CC0 Public Domain Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania Perelman School of Medicine pioneered a first of its kind gene therapy model that offers a potential breakthrough in treating X-linked sideroblastic anemia (XLSA), a rare congenital anemia caused by mutations in the ALAS2 gene...
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Brain study challenges long-held views about Parkinson’s movement disorders
by Niranjana Rajalakshmi, University of Arizona Credit: Pixabay/CC0 Public Domain University of Arizona researchers have revealed new insights into one of the most common complications faced by Parkinson’s disease patients: uncontrollable movements that develop after years of treatment. Parkinson’s disease—a neurological disorder of the brain that affects a person’s movement—develops when the level of dopamine, a...
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AI system helps doctors identify patients at risk for suicide
by Vanderbilt University Medical Center Credit: Pixabay/CC0 Public Domain A new study from Vanderbilt University Medical Center shows that clinical alerts driven by artificial intelligence (AI) can help doctors identify patients at risk for suicide, potentially improving prevention efforts in routine medical settings. A team led by Colin Walsh, MD, MA, associate professor of Biomedical Informatics,...