Highlights Fasting mimicking diet induces prenatal-development gene expression in adult pancreas FMD promotes Ngn3 expression to generate insulin-producing β cells Cycles of FMD reverse β-cell failure and rescue mice from T1D and T2D Inhibition of PKA or mTOR promotes Ngn3-driven β-cell regeneration in human T1D islets Summary Stem-cell-based therapies can potentially reverse organ dysfunction and...
Category: <span>Research Updates</span>
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Dietary supplement derived from tree bark shows promise for treating obstructive sleep apnea
Obstructive sleep apnea is caused by a narrowing of the airway that cuts off breathing, and people who are obese are at higher risk for the disorder. MIT researchers have discovered that a dietary supplement called yohimbine reverses the …more Obstructive sleep apnea, which causes people to briefly stop breathing while asleep, affects an estimated...
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Type 2 diabetes prevented in 80 per cent of at-risk patients thanks to repurposed drug
Prediabetes progresses into diabetes in 5-10 per cent of patients within ten years, say researchers. A weight loss drug has reduced the risk of type 2 diabetes by 80 per cent compared to placebo. The drug, which increases the amount of appetite-supressing hormones produced by the gut, was tested on overweight people with ‘prediabetes’. This...
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La Jolla’s low blood pressure treatment clears key study
Feb 27 (Reuters) – La Jolla Pharmaceutical Co said its lead experimental drug to treat low blood pressure met the main goal of a late-stage study on patients with distributive shock who have not adequately responded to existing treatments. Distributive shock is a state in which the heart is pumping well enough, but the blood...
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Login Saturday, Mar 31st 2018 9AM 37°C 12PM 31°C 5-Day Forecast ‘What is the best way to banish ingrown toenails?’ Our expert reveals how YOU can put an end to the painful problem for good
Amanda Chamberlain’s son has struggled with ingrown toenails for ten years She wonders if having the nail removed can keep the symptoms from returning My son is 19 and has had six or seven procedures to remove ingrown toenails on the big toe of his left foot. He’s had infections in that toenail more times...
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Vitamin-dispensing nanomesh designed to get on peoples’ nerves
The material could find use in the treatment of carpal tunnel syndrome For injuries in which nerves are severed, there are already conduits (basically tiny tubes) that can be used to hold the two ends together while they heal. These don’t actually do anything to promote healing, however, plus they can’t be used on nerves that...
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Magnetic implant puts the squeeze on drug delivery
A prototype “microspouter” with a Canadian dollar coin for scale When it comes to conditions such as diabetes, which require patients to administer daily injections or take lots of pills, scientists are increasingly looking to drug-dispensing implants as a more convenient alternative. One of the latest such devices, developed at the University of British Columbia, is...
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Scientists develop 'lab on a chip' that costs 1 cent to make
Rahim Esfandyarpour helped to develop a way to create a diagnostic “lab on a chip” for just a penny. Researchers at the Stanford University School of Medicine have developed a way to produce a cheap and reusable diagnostic “lab on a chip” with the help of an ordinary inkjet printer. At a production cost of...
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Nanofiber matrix sends stem cells sprawling in all directions
Human stem cells grown on Kyoto University’s “fiber-on-fiber” culturing system Mighty promising as they are, stem cells certainly aren’t easy to come by. Recent scientific advances have however given their production a much-needed boost, with a Nobel-prize winning technology that turns skin cells into embryonic-like stem cells and another that promises salamander-like regenerative abilities being just a couple...
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Immersive reality helps autistic kids deal with the real thing
The Blue Room is used to simulate catching a bus It’s not at all uncommon for autistic children to have phobias. Unfortunately, these fears can sometimes be so severe that the children have to completely avoid commonly-experienced situations such as taking buses or going into shops. A relatively new immersive reality treatment, however, is showing...