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Experts highlight new concepts and approaches to the rehabilitation of stroke

Stroke remains a leading cause of adult disability, and the global burden of stroke continues to grow with devastating consequences for patients, families, and caregivers. In this special issue of NeuroRehabilitation leading international experts on stroke rehabilitation provide theoretical and practical insights into the steps necessary to push beyond merely compensatory training and onto a level of...

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Team finds missing immune cells that could fight lethal brain tumors

Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body’s defenses. Researchers at Duke Cancer Institute have tracked the missing T-cells in glioblastoma patients in the bone marrow, locked away and unable to function because of a...

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New approach to treating chronic itch

UNIVERSITY OF ZURICH Two receptors in the spinal cord and the right experimental drug: Researchers at the University of Zurich have discovered a new approach that suppresses itch. In a series of experiments in mice and dogs they successfully alleviated different forms of acute as well as chronic itch. For the latter, current treatment options are very...

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Researchers assemble ‘library of sugars’

UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Most of us tend to think of sugar as a temptation that threatens our health. The reality is, however, that sugar is an essential component of the human body; it covers the surface of our cells and proteins and tunes the behavior and function of...

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New gene editing approach for alpha-1 antitrypsin deficiency shows promise

A new study by scientists at UMass Medical School shows that using a technique called “nuclease-free” gene editing to correct cells with the mutation that causes a rare liver disease leads to repopulation of the diseased liver with healthy cells. Alpha-1 antitrypsin deficiency is an inherited disease that causes liver and lung damage; the Mueller...

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New genome-editing strategy could lead to therapeutics

Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases, according to research published in the Aug. 18 edition of Nature Biotechnology. Credit: CC0 Public Domain First author Dan Wang, Ph.D., instructor in microbiology & physiological systems, together with co-corresponding authors Guangping Gao, Ph.D., the Penelope Booth...

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Can Stem Cell Fillings Replace a Root Canal Procedure?

Those who live in fear of the infamous root canal – maligned worldwide for its painful nature and disliked for the fact that it kills the tooth – will find relief in the news that researchers have found a promising alternative in the form of stem cell fillings. This approach relies on treating root causes and conditions...