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Exploring the heterogeneity of metabolic dysfunction-associated steatotic liver disease

by Deutsches Zentrum fuer Diabetesforschung DZD Credit: Norbert Stefan, IDM / DZD About 70% of obese people have metabolic dysfunction-associated steatotic liver disease (MASLD). However, MASLD is also found in lean people. Paradoxically, some effective pharmacological approaches to improve liver health in people with MASLD are associated with no change in body weight or even...

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Paper-based biosensor offers pain-free diabetes monitoring via sweat

by Chris Kocher, Binghamton University A new paper-based biosensor system uses bacterial spores that germinate in response to glucose in potassium-rich bodily fluids, such as sweat. Credit: Binghamton University Millions of people with diabetes track their glucose levels daily using finger-stick devices that draw and analyze their blood. But what if they could monitor it with...

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Diabetes drug linked to increased risk of severe eye condition

by Nana Olejank Hansen, University of Southern Denmark Credit: CC0 Public Domain Two independent studies from the University of Southern Denmark (SDU) show that patients with type 2 diabetes who are treated with the drug Ozempic have an increased risk of developing damage to the optic nerve of the eye, which can lead to severe and...

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Drugs to Target Lp(a): What’s Coming

Michelle L. O’Donoghue, MD, MPH; Stephen J. Nicholls, MBBS, PhD DISCLOSURES | December 13, 2024 Michelle L. O’Donoghue, MD, MPH: Hi. This is Dr Michelle O’Donoghue, reporting for Medscape. I’m here at the American Heart Association Scientific Sessions. It’s a very exciting meeting, but one of the interesting topics that we’re going to be talking about is lipoprotein(a) [Lp(a)] ....

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DGIST develops technology to stimulate the brain with an ultra-small coil

Peer-Reviewed Publication DGIST (Daegu Gyeongbuk Institute of Science and Technology) □ DGIST(President Kunwoo Lee) announced that a research team led by Prof. Kim So-hee from the Department of Robotics and Mechanical Electronics has developed a technology that enables precise brain stimulation using a coil small enough to be implanted in the body. It is expected...

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Hidden mechanism of swallowing revealed by Caenorhabditis elegans!

Peer-Reviewed Publication DGIST (Daegu Gyeongbuk Institute of Science and Technology) □ DGIST (President Kunwoo Lee) announced that a research team led by Professor Kim Kyuhyung at the Department of Brain Sciences has discovered a new principle that regulates how food moves through the digestive tract and is swallowed. They found that the Piezo channel proteins...

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Emotional cognition analysis enables near-perfect Parkinson’s detection

Peer-Reviewed Publication Intelligent Computing image:  The pipeline illustrates how EEG signals are processed for Parkinson’s disease detection. Key features are extracted from brainwave data and transformed into images or movie representations. These are then analyzed using machine learning models to classify emotional responses, high and low valence and arousal, and differentiate patients with Parkinson’s disease...

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Schizophrenia: Researchers observe disease processes in nerve cells

by Jörg Schäfer, NMI Naturwissenschaftliches und Medizinisches Institut in Reutlingen Example ICC images of marker expression in iPSC (left) and NPC (right) obtained by high-content microscopy. Credit: BMC Psychiatry (2024). DOI: 10.1186/s12888-024-06127-x Up to now, schizophrenia has mainly been treated symptomatically, as little is known about the exact underlying processes. Researchers at the NMI Natural and Medical...

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AI-powered blood test spots earliest breast cancer signs

A new screening method that combines laser analysis with a type of AI is the first of its kind to identify patients in the earliest stage of breast cancer, a study suggests. The fast, non-invasive technique reveals subtle changes in the bloodstream that occur during the initial phases of the disease, known as stage 1a,...

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Better Than Metformin: New Diabetes Wonder-Drug Slashes Fat and Blood Sugar

By Kumamoto UniversityDecember 14, 202484 Comments3 Mins Read FacebookTwitterPinterestTelegram Share HPH-15 offers multiple benefits for managing Type 2 diabetes, including effective blood glucose control, reduced risk of lactic acidosis, improved insulin resistance, and suppression of fat buildup and fibrosis in the liver and fat tissue, with these effects observed in studies using muscle, liver, and fat...