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Wearable Device Can Warn of Worsening Heart Failure

Carolyn Brown November 19, 2024 3182 Added to Email Alert A simple, lightweight device worn on the sternum can calculate intracardiac filling pressures, warning that heart failure is worsening, according to a study conducted to determine whether the device can produce the data needed. The developers are designing the CardioTag device to offer advantages over...

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Noninvasive imaging method can penetrate deeper into living tissue

Using high-powered lasers, this new method could help biologists study the body’s immune responses and develop new medicines. Adam Zewe|MIT News Publication Date: December 11, 2024  Press Inquiries Caption: The new technique enables laser light to penetrate deeper into living tissue, which captures sharper images of cells at different layers of a living system. On...

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Some aging cells heal wounds, others cause harm: Study shows how to distinguish between the two

by Kim Krieger, University of Connecticut Images showing the distribution of cells in the skin of intact (left) and wounded (right) mice. The colors represent different cell types. The black lines show the edges of the wound. Credit: University of Connecticut Lengthening life by eliminating old, inflammatory cells is a tantalizing idea, but anti-aging researchers suspect...

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Molecular insights unlock a targeted approach to cancer immunotherapy

by Monash University Human LAG-3 homodimer (with domains D1, D2, D3 and D4) binding to two separate HLA-II (MHC-II) molecules on the surface of an antigen-presenting cell (APC), imposing a distinct 38° offset angle. This figure has been modified from the original figure 1c of Petersen et al to aid visualization. Credit: Monash University Australian-led research...

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Prenatal SSRI exposure linked to functional constipation in offspring

by Elana Gotkine Prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) is associated with an increased risk of functional constipation developing in offspring, according to a study published online Dec. 10 in Molecular Psychiatry. Helene Kildegaard, M.D., from the Hans Christian Andersen Children’s Hospital in Odense, Denmark, and colleagues examined associations between gestational SSRI exposure and...

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Japanese researchers test pioneering drug to regrow teeth

by Tomohiro OSAKI Handout images from the Medical Research Institute Kitano Hospital show before (top) and after images of the regrowth of teeth in a ferret (centre) and mice (R and L). People with missing teeth may be able to grow new ones, say Japanese dentists testing a pioneering drug they hope will offer an...

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New immunotherapy platform has increased potential to target cancer cells

by Children’s Hospital of Philadelphia Credit: Unsplash/CC0 Public Domain Researchers from Children’s Hospital of Philadelphia (CHOP) and Stanford University have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better understanding of its structure may help optimize designs for the platform, which can be used to develop cancer treatments by either...

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Noninvasive imaging method can penetrate deeper into living tissue

Using high-powered lasers, this new method could help biologists study the body’s immune responses and develop new medicines. Adam Zewe|MIT News Publication Date: December 11, 2024  Press Inquiries Caption: The new technique enables laser light to penetrate deeper into living tissue, which captures sharper images of cells at different layers of a living system. On...

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Do GLP-1s Lower VTE Risk in People With Type 2 Diabetes?

Kate Johnson December 11, 2024 03 Added to Email Alert Glucagon-like peptide 1 (GLP-1) receptor agonists led to a significant reduction in the risk for venous thromboembolism (VTE) among individuals with type 2 diabetes compared with dipeptidyl peptidase 4 (DPP-4) inhibitors, a recent analysis indicated. Overall, GLP-1 agonist use was associated with a 20% reduction...

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Sleep Apnea Linked to Heightened Mortality in Epilepsy

Jim Kling December 10, 2024 07 Added to Email Alert LOS ANGELES — Individuals with both uncontrolled epilepsy and sleep apnea are at significantly higher risk for mortality than those with epilepsy alone, according to a new analysis of over 2 million patient-years drawn from the Komodo Health Claims Database. “A 10-year-old with uncontrolled central...