61 Added to Email Alert 00:0004:30 Hello. This is Dr JoAnn Manson, professor of medicine at Harvard Medical School and Brigham and Women’s Hospital. I’d like to talk with you about a recent report in the British Medical Journal (BMJ) on different forms of contemporary menopausal hormone therapy and risks for cardiovascular disease (CVD). This is a very large-scale and comprehensive...
Category: <span>Research Updates</span>
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Micro-flowers” may one day deliver life-saving drugs within the body
By Ben Coxworth December 12, 2024 A batch of the drug-delivery microparticles – these ones are made of zinc oxide, although other materials can be used Dong Wook Kim / Max Planck Institute for Intelligent Systems, colorization: ETH Zurich View 3 Images View gallery – 3 images Whether a medication is taken orally or intravenously, it...
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Tetanus vaccine delivered by skin cream instead of needle
By Michael Irving December 12, 2024 In the future, getting a vaccine could be as simple and painless as rubbing on some skin cream Depositphotos View 1 Images If you were given a choice of vaccine delivery method, would you rather a needle or a skin cream? Thought so. Well, the latter might be a viable...
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Eye Toxicities Are a Growing Concern With Certain ADCs
Liam Davenport December 11, 2024 5349 Added to Email Alert Despite being a targeted therapy, antibody-drug conjugates (ADCs) can cause significant off-target toxicity to the eyes of patients being treated for advanced multiple myeloma or cervical cancer, yet the risks remain relatively unknown, according to oncologists and ophthalmologists. Such experts called for greater collaboration between...
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Tiny sensors offer new hope for faster bone injury recovery
by Rachel Lukowicz-Bedford, University of Oregon Kylie Williams and Bob Guldberg look at the way resistance training can improve bone regeneration after a major injury, specifically measuring bone strain over the course of healing. Credit: University of Oregon Tiny implantable sensors are helping University of Oregon researchers optimize the process of recovery from severe bone injuries....
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Beyond batteries: Researchers bring body-heat powered wearable devices closer to reality
by Queensland University of Technology Credit: AI-generated image A QUT-led research team has developed an ultra-thin, flexible film that could power next-generation wearable devices using body heat, eliminating the need for batteries. This technology could also be used to cool electronic chips, helping smartphones and computers run more efficiently. Professor Zhi-Gang Chen, whose team’s research was published in Science,...
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Lentiviral vectors offer gene therapy option for hemophilia A patients with anti-AAV antibodies
by Justin Jackson , Medical Xpress Credit: Pixabay/CC0 Public Domain Research led by Christian Medical College in Vellore, India, has demonstrated the successful use of lentiviral vectors to deliver gene therapy for patients with severe hemophilia A. The study presents a potential alternative to adeno-associated virus (AAV)-mediated gene therapy, addressing the exclusion of patients with...
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Unexpected Findings in Study of T Cells, Considered Front-line Fighters Against Advanced Melanoma
Posted Today Yale researchers made an unexpected discovery—turncoat T cells that help a tumor evade other cancer-fighting immune T cells—in a study of patients living with advanced melanomathat was published in Nature Immunology. Melanoma cells – artistic impression. Image credit: Gemini / Alius Noreika The study by Yale Cancer Center (YCC) researchers at Yale School of Medicine (YSM)...
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For the first time, researchers detect pre-malignant pancreatic lesions with magnetic resonance imaging
Peer-Reviewed Publication Champalimaud Centre for the Unknown image: MRI microscopy of mouse and human pancreas with respective histology, demonstrating the ability of DTI maps (Fractional anisotropy and Axial diffusivity) to identify pre-malignant lesions (black arrows). The white arrows point to foci of adenocarcinoma.view more Credit: Adapted from Bilreiro C, et al. Investigative Radiology, 2024 Precursor lesions...
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Light-induced gene therapy disables cancer cells’ energy center
In study, targeted delivery shrinks brain, breast tumors in micePeer-Reviewed Publication Ohio State University COLUMBUS, Ohio – Researchers are shining a light on cancer cells’ energy centers – literally – to damage these power sources and trigger widespread cancer cell death. In a new study, scientists combined strategies to deliver energy-disrupting gene therapy using nanoparticles...