Minuscule Robots for Targeted Drug Delivery December 11, 2024 In the future, delivering therapeutic drugs exactly where they are needed within the body could be the task of miniature robots. Not little metal humanoid or even bio-mimicking robots; think instead of tiny bubble-like spheres. Such robots would have a long and challenging list of requirements....
Category: <span>Research Updates</span>
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Neurosurgeons unravel the distinct nerve wiring of human memory
by Institute of Science and Technology Austria Human CA3 pyramidal neurons recorded in a patient tissue sample. Credit: Jake Watson The black box of the human brain is starting to open. Although animal models are instrumental in shaping our understanding of the mammalian brain, scarce human data is uncovering important specificities. In a paper published in Cell, a team...
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First full characterization of kidney microbiome unlocks potential to prevent kidney stones
Low levels of bacteria like E. coli and Lactobacillus in our urine come from communities in our kidneys, where they promote or prevent kidney stone formationPeer-Reviewed Publication Cleveland Clinic Cleveland Clinic researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating that the urinary tract is not sterile and...
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Breakthroughs in cell-penetrating monoclonal antibody therapies
“Monoclonal antibodies (mAb) have emerged as a promising tool in advancing personalized medicine”Peer-Reviewed Publication Impact Journals LLC image: Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical...
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Persistent tobacco smoking from childhood may cause heart damage by the mid-twenties
Peer-Reviewed Publication University of Eastern Finland image: In 1931 children followed up from age 10 to 24 years, persistent tobacco smoking from childhood through young adulthood caused structural and functional heart damage. Tobacco smoking excessively increases heart mass during growth from adolescence to young adulthood. Image: Andrew Agbaje.view more Credit: Andrew Agbaje The majority of children...
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NIH research reveals new insights about how ‘bad’ cholesterol works in the body – cardiology
Findings could pave the way for more personalized treatments for cardiovascular diseasePeer-Reviewed Publication NIH/National Heart, Lung and Blood Institute National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how “bad” cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time...
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Innovative tissue engineering: Boston University’s ESCAPE method explained
Molding complex tissues using galliumPeer-Reviewed Publication Boston University When it comes to the human body, form and function work together. The shape and structure of our hands enable us to hold and manipulate things. Tiny air sacs in our lungs called alveoli allow for air exchange and help us breath in and out. And tree-like...
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Stanford scientists transform ubiquitous skin bacterium into a topical vaccine
Peer-Reviewed Publication Stanford Medicine Imagine a world in which a vaccine is a cream you rub onto your skin instead of a needle a health care worker pushes into your one of your muscles. Even better, it’s entirely pain-free and not followed by fever, swelling, redness or a sore arm. No standing in a long...
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Scientists discover new receptor for nerve growth factor—a promising target for treating pain
by New York University Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Credit: Bunnett Lab Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does...
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Understanding how the immune system switches between rest and action
Scientists at Gladstone and UCSF discover how one protein controls the behavior of immune cells, with potential applications for treating cancer and autoimmune conditionsPeer-Reviewed Publication Gladstone Institutes image: Scientists at Gladstone and UC San Francisco—including Maya Arce, seen here—discover how one protein controls the behavior of immune cells, with potential applications for treating cancer and...