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New GFR formula offers better diagnosis of hyperfiltration in elderly patients

 Reviewed Osaka Metropolitan UniversityJan 6 2025 Annual health checkups regularly include urine tests that serve several purposes, including checking for symptoms of kidney disease. The presence of albumin in the urine is one indicator as is glomerular filtration rate. In diabetic nephropathy, albuminuria first appears, leading to excessive filtration and eventually a decrease in GFR....

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ELECTRONIC TATTOO DECODES BRAINWAVES

JANUARY 3RD, 2025POSTED BY UT AUSTIN (Credit: UT Austin) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY  UNIVERSITY OF TEXAS AT AUSTIN A new conductive ink can be printed directly on the surface of a patient’s head and measure their brainwaves. Since the emergence of temporary, skin-attached...

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SCIENCE & TECHNOLOGY NEWS

Uncovering why some seizures cause loss of consciousness Posted Yesterday In temporal lobe epilepsy — a common and debilitating form of the disorder — seizures often cause those affected to lose consciousness. But why that happens has been unclear. Brain stimulation – artistic interpretation. In a new study, Yale researchers show that levels of acetylcholine, a neurotransmitter that plays...

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Labeling cell particles with barcodes

Posted Today Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. The particles, known as small extracellular vesicles (sEVs), play an important role in the spread of disease and as potential drug carriers.  The newly developed system,...

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Gene expression study reveals human brain cell types becoming more specialized, not just more numerous

by Harrison Tasoff, University of California – Santa Barbara Differences in gene expression, not just their presence, seem to drive the remarkable specialization found in the human brain. Credit: Matt Perko Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other...

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Urinary Metals Linked to Increased Dementia Risk

Edited by Anushree Chaphalkar December 31, 2024 0130 TOPLINE: Higher levels of environmental metals in urine are associated with poorer cognitive performance and an increased risk for dementia, new research suggests. METHODOLOGY: TAKEAWAY: IN PRACTICE: “We found an inverse association of essential and nonessential metals in urine, both individually and as a mixture, with the...

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Achilles Heel’ of Drug-Resistant Bacteria Has Been Found, Scientists Say

Health30 December 2024 ByTessa Koumoundouros Bacillus subtilis bacteria with green fluorescence indicating a lack of magnesium. (Ashley Moon, Süel Lab, UC San Diego) New tactics in controlling infection are sorely needed, with antibiotic-resistant bacteria expected to claim as many as 2 million lives each year by 2050. US and Spanish researchers have now discovered at least some bacteria pay...

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Can We Stop Brain Aging? Scientists Uncover Mitochondrial Key

By American Association for the Advancement of ScienceJanuary 1, 20253 Comments3 Mins Read FacebookTwitterPinterestTelegram Share Researchers uncovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) linking neuronal activity to mitochondrial DNA transcription, crucial for maintaining brain function. Enhancing E-TCmito in aged mice improved cognition, offering a potential therapeutic target for age-related cognitive decline and neurodegenerative diseases....

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Y chromosome’s unexpected impact on aging and disease in men

By Priyanjana Pramanik, MSc.Reviewed by Susha Cheriyedath, M.Sc.Jan 5 2025 Why losing the Y chromosome is more than genetics—it’s a key to understanding male health disparities. Review Article: The effects of loss of Y chromosome on male health. Image Credit: Rost9 / Shutterstock In a recent review article in the journal Nature Reviews Genetics, researchers discussed the current understanding regarding the...

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Impact of exosomal and cell-free circRNAs on cancer drug resistance

Peer-Reviewed Publication ELSP The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance. In order to propagate malignancy, circRNAs shuttle through the blood circulation as cell-free molecules or in exosomes, small vesicles where they are transported to various cells. Published in ExRNA, the...