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A Rare Win for Vitamin D — This Time in MS

F. Perry Wilson, MD, MSCE DISCLOSURES | March 10, 2025 17451 00:0008:34 This transcript has been edited for clarity.  Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson from the Yale School of Medicine. Study after study across diseases, from Alzheimer’s disease to Zika virus infection, has shown that low vitamin D level...

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Protein from small intestine may hold key to obesity treatment

by Ohio University Lipid accumulation in the livers of high-fat diet (HFD)-fed mice. Credit: Obesity (2024). DOI: 10.1002/oby.24155 A team of Ohio University researchers have made a groundbreaking development in the fight against obesity. In a study recently published in Obesity, the researchers highlight a protein that is naturally produced in the body but could potentially be applied to combat weight...

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Diterpene-based drug achieves functional neuronal regeneration after brain injury in preclinical study

by University of Seville EOF2 administration promotes migration of neuroblast from the SVZ to cortical injury within 14 days. Credit: Stem Cell Research & Therapy (2025). DOI: 10.1186/s13287-024-04105-4 Researchers from the University of Seville and the University of Cadiz, coordinated by the professors of Physiology Pedro Núñez-Abades and Carmen Castro, have demonstrated that the use of diterpenes facilitates repopulation...

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20-year study is the first to show food insecurity raises risk of heart disease over time

by Northwestern University Credit: Pixabay/CC0 Public Domain Struggling to afford food today could mean heart problems tomorrow. Young adults experiencing food insecurity have a 41% greater risk of developing heart disease in midlife, even after accounting for demographic and socioeconomic factors, according to a new Northwestern Medicine study. Food insecurity—struggling to get enough nutritious food to...

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Exoskeleton and digital twin speed up stroke recovery

by Technical University Munich Wolfgang Korisanski is one of the 24 patients who have already tested the new exoskeleton and electrical stimulation system for a study. In the background: Hossein Kavianirad (left) and Neha Das, researchers from Prof. Sandra Hirche’s department. Credit: Sabrina Bauer / TUM Researchers at the Technical University of Munich (TUM) have developed...

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Some animals’ natural biological defenses could inspire new approaches to cancer prevention and treatment in humans

by Richard Harth, Arizona State University A new study analyzing diet, average plasma sugar levels and cancer prevalence in some 273 vertebrate species showed surprising results. The study found no significant link between diet and plasma sugar levels across nonhuman vertebrate species, suggesting that glucose regulation is likely influenced more by evolutionary and physiological adaptations than...

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Monoclonal antibody significantly reduces nasal polyps and need for surgery in Phase 3 clinical trial

by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain Chronic rhinosinusitis with nasal polyps presents a substantial clinical burden, affecting nasal airflow, olfactory function, and quality of life. Epithelial barrier dysfunction and type 2 inflammatory responses drive disease progression. Treatments such as intranasal glucocorticoids and sinus surgery provide limited long-term relief and fail to...

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Molecular differences in pancreatic cancer of Black and white patients identified

by Henry Ford Health Ling Huang, Ph.D. performs research work at the Henry Ford Health Pancreatic Cancer Center in Detroit. Credit: Henry Ford Health Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic cancer respond to immunotherapies. The findings, which were recently published in the journal Cancer Research Communications, reinforce the...

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Targeted alpha therapy offers new hope for treating metastatic melanoma

 Reviewed Chiba UniversityMar 12 2025 Metastatic melanoma, also known as stage IV melanoma, is a type of skin cancer that spreads to other parts of the body. It is one of the most aggressive forms of skin cancer, with current therapies—including immunotherapy and targeted drugs—showing limited effectiveness. Radiotherapy is an emerging treatment for melanoma, but conventional beta-emitting radionuclide...

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New device developed to non-invasively break up kidney stones

 Reviewed Universitat Politècnica de ValènciaMar 12 2025 A team from the Universitat Politècnica de València (UPV) and the Spanish National Research Council (CSIC), belonging to the Research Institute for Molecular Imaging Technologies (I3M), has developed, together with the NITIUV Group of the La Fe Health Research Institute (IIS La Fe) in Valencia and the Biomechanics...