by Tel-Aviv University Differential effects of TIMM50 mutation on the expression of TIM23, PAM and TOM subunits and matrix-destined proteins. Credit: eLife (2024). DOI: 10.7554/eLife.99914.2 Researchers at Tel Aviv University have developed an innovative research model that allowed them to decode the mechanism underlying a severe and rare neurological disease. The disease is characterized by symptoms such as...
Category: <span>Research Updates</span>
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MASH discovery redefines subtypes with distinct risks: shaping the future of fatty liver disease treatment
Peer-Reviewed Publication INSERM (Institut national de la santé et de la recherche médicale) Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population. The disease spans from benign fat accumulation in the liver (steatosis) to its more severe form, metabolic dysfunction-associated steatohepatitis...
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Study links high-fiber diet to delayed progression of blood cancer
by Memorial Sloan Kettering Cancer Center Credit: Unsplash/CC0 Public Domain Researchers at Memorial Sloan Kettering Cancer Center (MSK) have reported results from the first-ever clinical trial demonstrating that a high-fiber, plant-based dietary intervention may delay progression to multiple myeloma, a rare and incurable blood cancer affecting the bone marrow. The study enrolled 20 participants with a precancerous blood...
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New AI stroke brain scan readings are twice as accurate as current method
by Samantha Rey06 December 2024 view large AI pinpoints stroke timing, treatment potential from a single scan New AI software can read the brain scans of patients who have had a stroke, to more accurately pinpoint when it happened and help doctors work out whether it can be successfully treated. It is hoped that the new...
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Neuroscientists discover a new pathway to forming long-term memories in the brain
by Max Planck Florida Institute for Neuroscience Scientists discover a new pathway to long-term memory formation in the brain that can bypass the formation of short-term memory. Credit: Helena Pinheiro Researchers from Max Planck Florida Institute for Neuroscience have discovered a new pathway to forming long-term memories in the brain. Their work, published in Nature Neuroscience, suggests that long-term...
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Repurposed drug has promising efficacy in non-small cell lung cancer
by UT Southwestern Medical Center UT Southwestern researchers (l-r) Farjana Fattah, Ph.D., Mitchell S. von Itzstein, M.D., David E. Gerber, M.D., and Kelly Kyle, B.S., discovered a drug that shows promise in treating non-small cell lung cancer with KRAS mutations. Credit: UT Southwestern Medical Center An FDA-approved drug used to treat multiple myeloma and lymphoma also shrank tumors in...
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LBCL: Bispecific Antibodies Fare Less Well in Real-World Analysis
Randy Dotinga December 07, 2024 01 SAN DIEGO — Compared with clinical trials, a real-world retrospective analysis has linked the bispecific antibodies epcoritamab (Epkinly) and glofitamab (Columvi) to somewhat poorer outcomes in relapsed or refractory large B-cell lymphoma (LBCL). In a presentation here at the American Society of Hematology (ASH) 2024 Annual Meeting, researchers reported that of 172 patients treated with the...
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Common thyroid drug levothyroxine linked to bone mass loss
Share on PinterestCould a commonly prescribed thyroid drug lead to bone loss? Image credit. Willie B. Thomas/Getty Images. Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown. Researchers from Johns Hopkins University School of Medicine in...
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Remote-controlled gene therapy uses ultrasound to kill cancer
By Michael Irving December 09, 2024 An artist’s impression of CRISPR getting to work on cancer cells with the help of ultrasound pulses Wang Lab and Pepper Workshop View 1 Images A new kind of cancer gene therapy can be remotely activated at a specific part of the body. The team developed a version of CRISPR...
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One type of blood pressure med may help prevent post-stroke epilepsy
by Dennis Thompson Some people develop epilepsy after surviving a stroke, as the injury they’ve sustained causes scarring and disorganized electrical activity in their brains. But one type of blood pressure medication seems to help stroke survivors avoid post-stroke epilepsy (PSE), according to a first-of-its-kind study presented Friday at the annual meeting of the American Epilepsy...