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Study details how ketones improve blood flow to the heart

by Masonic Medical Research Institute Credit: Pixabay/CC0 Public Domain A research team led by Matthew Nystoriak, Ph.D., associate professor of biomedical research and translational medicine at Masonic Medical Research Institute (MMRI), has uncovered groundbreaking insights into heart health in a study titled “Myocardial Hyperemia via Cardiomyocyte Catabolism of β-Hydroxybutyrate.” The research highlights how a ketone body called β-hydroxybutyrate...

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Streamlined approach to testing for heparin-induced thrombocytopenia improves diagnostic accuracy

by Association for Diagnostic and Laboratory Medicine Relationship between HIT ELISA % heparin inhibition, low-heparin OD, and SRA results for nonnegative HIT ELISAs with corresponding SRA testing during the analysis period (December 7, 2016–December 31, 2021). Credit: The Journal of Applied Laboratory Medicine (2025). DOI: 10.1093/jalm/jfae131 A new study appearing in The Journal of Applied Laboratory Medicine (JALM) has found that...

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Genetically altered fat cells in mice show promise for obesity treatment

by UT Southwestern Medical Center Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.11.003 Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study. Published in Cell Metabolism, the...

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Genetic discovery offers hope for personalized epilepsy treatments

by Laura Frnka-Davis, University of Texas Health Science Center at Houston In silico sequence- and structure-based analysis of variants in candidate genes. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-54911-w Recent research led by UTHealth Houston scientists has uncovered two genes associated with variants linked to epilepsy, which showed specific traits that make them promising diagnostic biomarkers. The study is published in Nature...

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Why don’t new memories overwrite old ones? Sleep science holds clues

Research in mice points towards a mechanism that avoids ‘catastrophic forgetting’. Artificially coloured nerve fibres in a mouse’s hippocampus, the brain region where new memories are encoded.Credit: Mark & Mary Stevens Neuroimaging & Informatics Institute/Science Photo Library New clues have emerged in the mystery of how the brain avoids ‘catastrophic forgetting’ — the distortion and...

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New GFR formula offers better diagnosis of hyperfiltration in elderly patients

 Reviewed Osaka Metropolitan UniversityJan 6 2025 Annual health checkups regularly include urine tests that serve several purposes, including checking for symptoms of kidney disease. The presence of albumin in the urine is one indicator as is glomerular filtration rate. In diabetic nephropathy, albuminuria first appears, leading to excessive filtration and eventually a decrease in GFR....

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ELECTRONIC TATTOO DECODES BRAINWAVES

JANUARY 3RD, 2025POSTED BY UT AUSTIN (Credit: UT Austin) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY  UNIVERSITY OF TEXAS AT AUSTIN A new conductive ink can be printed directly on the surface of a patient’s head and measure their brainwaves. Since the emergence of temporary, skin-attached...

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SCIENCE & TECHNOLOGY NEWS

Uncovering why some seizures cause loss of consciousness Posted Yesterday In temporal lobe epilepsy — a common and debilitating form of the disorder — seizures often cause those affected to lose consciousness. But why that happens has been unclear. Brain stimulation – artistic interpretation. In a new study, Yale researchers show that levels of acetylcholine, a neurotransmitter that plays...

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Labeling cell particles with barcodes

Posted Today Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. The particles, known as small extracellular vesicles (sEVs), play an important role in the spread of disease and as potential drug carriers.  The newly developed system,...