Peer-Reviewed Publication Marine Biological Laboratory image: Electron microscope image of a cryo-preserved axon shows details of its pearls-on-a-string nanomorphology. Credit: Quan Gan and Mitsuo Sugaview more Credit: Quan Gan and Mitsuo Suga WOODS HOLE, Mass. — In a provocative new study, scientists challenge a fundamental tenet in neuroscience about the shape of axons — the long,...
Category: <span>Research Updates</span>
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Discovering the mechanism behind brain’s inhibition network: From vision to action control
A new study reveals how key brain regions regulate inhibitory actions, paving the way for impulse control disorder treatmentPeer-Reviewed Publication Juntendo University Research Promotion Center image: Advanced brain imaging reveals how key regions work together to control impulses, paving the way for new treatments for impulsive disordersview more Credit: Dr. Takahiro Osada from Juntendo University, Japan...
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Evaluating long-term survival and cardiac efficacy of a gene therapy for Duchenne muscular dystrophy
by Mary Ann Liebert, Inc Fibrotic remodeling in skeletal muscle and heart of DMDMDX rats and impact of delandistrogene moxeparvovec treatment. A recent study published in the journal Human Gene Therapy evaluated the long-term survival and cardiac efficacy of the gene therapy delandistrogene moxeparvovec in a rat model of Duchenne muscular dystrophy (DMD). Delandistrogene moxeparvovec uses an adeno-associated viral (AAV) vector...
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Research shows dupilumab effective in treatment of children with atopic dermatitis
by National Jewish Health Credit: CC0 Public Domain Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another inflammatory condition, such as asthma, allergic rhinitis or food allergies. Dupilumab had previously been shown to...
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MDMA-assisted therapy could improve neurorehabilitation of injured service members beyond PTSD
by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain A UCLA Health analysis of MDMA-assisted therapy research suggests that the drug could improve outcomes of treatment of a wider range of trauma-related conditions experienced by military personnel beyond the current focus on post-traumatic stress disorder (PTSD) by increasing a collaborative and trusting relationship between a...
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Predictive model identifies at-risk patients who may need stomach cancer screening
by Cleveland Clinic Credit: Pixabay/CC0 Public Domain Cleveland Clinic developed a predictive model to identify patients at risk of developing gastric (stomach) cancer who may benefit from stomach cancer screening. The model is designed to identify who might need regular upper endoscopies to screen for stomach cancer. Although U.S. patients get routinely screened for other diseases,...
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Sex differences in neuron protection could reveal Alzheimer’s target
by Jim Schnabel, Cornell University Biological sex modulates responses to demyelination with age or disease pathology through Tlr7. Credit: Science (2024). DOI: 10.1126/science.adk7844 Inhibiting TLR7, an immune signaling protein, may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer’s disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine....
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New hypothesis on chronic inflammation could lead to advances in disease treatment
by Wayne State University Schematic presentation of the pathways leading to acute and chronic inflammation and unalamation. Credit: Frontiers in Immunology (2024). DOI: 10.3389/fimmu.2024.1460302 A recently published study led by Wayne State University on a new approach to understanding chronic inflammation could lead to new advancements in the treatment of many debilitating medical conditions, including cancer. The study,...
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Parkinson’s Disease Could Have a Simple Treatment, Study Finds
The simple fix? Vitamin B supplementation. By Sammi Caramela December 3, 2024, 12:05pm (Illustration via ChrisChrisW / Getty Images) Share: New research has found that Parkinson’s disease might just be linked to bacteria in the gut, suggesting promising treatment options. Parkinson’s disease is a neurodegenerative disorder that leads to slow-progressing symptoms like tremors, limb stiffness, postural instability, delayed...
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Unexpected discovery revives abandoned breast cancer treatment
by Lund University Molecular analyses of IGFBP7 expression in I-SPY2 and SCAN-B. Credit: npj Precision Oncology (2024). DOI: 10.1038/s41698-024-00712-9 A recent study led by Lund University in Sweden has found that some patients with aggressive breast cancer can be helped by a targeted cancer treatment that had been under development but was shelved. The study is important since...