by Tampere University On the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains the cytoplasm and proteins red or pink. This method is used in the diagnosis of prostate cancer. Visium technology (in the centre) allows...
Category: <span>Research Updates</span>
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The anatomy of a hot flush. Can it really make your head steam?
by Michelle Spear, The Conversation Credit: Pixabay/CC0 Public Domain A hot flush is a phenomenon as disruptive as it is commonplace. One moment, life proceeds as usual. The next, a wave of heat rises, spreading from the chest to the face—leaving behind flushed skin and beads of sweat. For many, this sudden warmth is accompanied by...
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Common heart drug may slow progression of Huntington’s disease
by University of Iowa β-Blocker Use in Participants With Motor-Manifest Huntington Disease (mmHD) Was Associated With Slower Rate of Symptom Progression. Credit: JAMA Neurology (2024). DOI: 10.1001/jamaneurol.2024.4108 A common heart drug may slow the progression of Huntington’s disease (HD), according to a new study by University of Iowa Health Care researchers. Using clinical information from a large, observational...
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Parasite-inspired medical devices
Peer-Reviewed Publication PNAS Nexus video: High-speed device triggering footage. Shot on a Phantom v1612 (FPS = 8000, aperture time = 120 µs, Extreme Dynamic Range (EDR) = 60 µs).view more Credit: Maquignaz et al. Inspired by the diverse attachment organs of parasites, researchers have designed a millimeter-scale mechanism for soft tissue anchoring. Robert J. Wood and colleagues...
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Severe COVID-19 may be a risk factor for multiple sclerosis
by Örebro Universitet Credit: CC0 Public Domain COVID-19 may be a risk factor for multiple sclerosis (MS). This has been shown by new research at Örebro University and Örebro University Hospital, Sweden. The study is published in the journal Brain Communications. “We saw a raised risk of MS among people who had severe COVID-19. However, only an extremely...
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Deep learning enhances gait analysis for spinal deformity detection
by University of Tsukuba An overview of the proposed method. Credit: IEEE Access (2024). DOI: 10.1109/ACCESS.2024.3479165 Evaluating human gait and posture is a clinically effective method for the early diagnosis of diseases involving gait afflictions, such as adult spinal deformity (ASD). Researchers at University of Tsukuba, Japan developed a method for classifying ASD based on the characteristics of...
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Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer
by The Hospital for Sick Children Model for PIEZO mechanosensing of the ISC niche. Credit: Science (2024). DOI: 10.1126/science.adj7615 A new study from The Hospital for Sick Children (SickKids) and Institut Curie reveals how stem cells sense and respond to their environment, with implications for inflammatory bowel disease and colorectal cancer. Stem cells constantly adapt to their environment...
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New theory suggests aging is driven by degenerative metabolic reprogramming over time
by Frontiers Journals Schematic illustration of the PAMRP theory of aging. Credit: Engineering (2024). DOI: 10.1016/j.eng.2024.09.010 Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called pro-aging metabolic reprogramming (PAMRP), which could change our understanding of aging. The traditional debate on aging has centered around whether it is a programmed...
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Surface protein study highlights a potential link between dental caries and renal lesions
by Okayama University Researchers from Okayama University, Japan, uncover novel pathogenic role of a surface collagen-binding protein “Cnm,” on Streptococcus mutans, a dental caries-causing bacteria, in the development of IgAN. Their findings open avenues for novel therapeutic interventions targeting dental caries to improve kidney health in patients with IgAN. Credit: Dr. Shuhei Naka, Okayama University https://www.nature.com/articles/s42003-024-06826-x IgA nephropathy (IgAN)...
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How stray DNA trips an immune alarm
A conversation with Andrea Ablasser, laureate of the 2024 Liliane Bettencourt Prize for Life Sciences. Produced by The cGAS–STING pathway senses and regulates the cellular response towards microbial and host-derived DNAs.Credit: byakkaya/ Getty Images Andrea Ablasser, an immunologist and laboratory head at the Swiss Federal Institute of Technology Lausanne in Switzerland, leads a team that...