Miriam E. Tucker November 26, 2024 115 Added to Email Alert WASHINGTON — Glucagon-like peptide 1 receptor agonist (GLP-1 RA) medications appear beneficial for people with systemic lupus erythematosus (SLE) and lupus nephritis, two new studies suggest. “The risk of cardiovascular disease is thought to be at least double that for people with lupus…and we...
Category: <span>Research Updates</span>
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First new treatment for asthma and COPD in half a century—new study
by Mona Bafadhel, Richard Russell and Sanjay Ramakrishnan, The Conversation Credit: Pixabay/CC0 Public Domain Every 30 seconds, someone in the world will experience a flare-up of their asthma or chronic obstructive pulmonary disease (COPD) symptoms. For decades, the standard treatment for these potentially life-threatening episodes has remained unchanged—treatment with steroids, such as prednisolone. Unfortunately, these drugs don’t...
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Study shows AI and physicians have equal difficulty identifying crackles when analyzing breath sounds
by National Taiwan University Comparison of ROC curves between human and All-data AI model in different breath sound identification. Credit: npj Primary Care Respiratory Medicine (2024). DOI: 10.1038/s41533-024-00392-9 Although crackles have long been regarded as a hallmark finding in physical examinations, a new study has revealed their unreliability not only among human physicians but also in artificial...
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Cerebral stroke in animal models with hypertension found to affect arteries in other body regions
by Autonomous University of Barcelona Credit: Life Sciences (2024). DOI: 10.1016/j.lfs.2024.123247 A study coordinated by Dr. Francesc Jiménez-Altayó, researcher at the Institut de Neurociències of the UAB (INc-UAB) and at CIBERCV, shows that temporary lack of blood flow to the brain can lead to lasting changes in the small arteries of the abdomen in rats with high blood...
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Enhancing the efficacy of cell transplantation therapy for stroke or traumatic brain injury
by Kyoto University Credit: Stem Cells Translational Medicine (2024). DOI: 10.1093/stcltm/szae066 Researchers have developed a technique to enhance the effectiveness of cell transplantation therapy for stroke or traumatic brain injury. The team, including Professor Jun Takahashi, Researcher Bumpei Samata, and Graduate Student Keitaro Yamagami from the Department of Clinical Application at CiRA, published their study in the journal Stem Cells Translational...
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New data could help Merck expand use of cardiovascular drug
Positive results from a study of Winrevair could help the drugmaker achieve sales growth past top-seller Keytruda’s upcoming patent expirations this decade. Published Nov. 25, 2024 Jonathan GardnerSenior Reporter Merck announced on Nov. 25, 2024, that its pulmonary arterial hypertension drug Winrevair succeeded in a clinical trial. Marko Georgiev / Stringer via Getty Images Dive Brief:...
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Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
by Verena Schulz, Helmholtz Association of German Research Centres Visualization of SARS-CoV-2 viral tropism in whole mouse bodies and SARS-CoV-2 spike protein persistency in skull marrow and brain. (A–E) SARS-CoV-2-GFP aerosol infection in K18-hACE2 mice. (A) Illustration of SARS-CoV-2-GFP infection and imaging of whole mouse body. (B) 3D reconstruction of whole mouse body showing localization of...
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AI can predict neuroscience study results better than human experts, study finds
by University College London Credit: Pixabay/CC0 Public Domain Large language models, a type of AI that analyzes text, can predict the results of proposed neuroscience studies more accurately than human experts, finds a study led by UCL (University College London) researchers. The findings, published in Nature Human Behaviour, demonstrate that large language models (LLMs) trained on vast...
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Bacteria ditch tags to dodge antibiotics
Modified ribosomes could be a new possible mechanism of antibiotic resistancePeer-Reviewed Publication Center for Genomic Regulation image: Colourised scanning electron micrograph of Escherichia coli, grown in culture and adhered to a cover slip.view more Credit: NIAID Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications. The subtle changes...
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Scientists find cause of rare devastating, autoimmune disease in Puerto Ricans—but also find potential treatment
by Delthia Ricks , Medical Xpress DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH A rare autoimmune condition with a tongue-twister of a name may impact people of Puerto Rican heritage through a newly discovered genetic pathway, a discovery that may ultimately guide genetic counseling and treatment, scientists...