Dear all, We would like to communicate about the transition of our physical rehabilitation from Hussain Aslan to Luke Marinkovich. Luke Marinkovich is a physical rehabilitation specialist who helped us develop and start the Brain & Gait program at our office back in December 2020. Luke and his team are experienced Kinesiologists in several aspects...
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How can diabetes affect the feet?
Diabetes, especially poorly controlled diabetes, can cause nerve damage and poor circulation. This can lead to foot ulcers, blisters, pain, and foot infections. In some cases, the damage can be severe. Infections in the feet can spread, damaging other organs and even becoming life threatening. Severe foot infections may mean a doctor has to amputate...
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What to know about Parkinson’s hallucinations
Parkinson’s disease most commonly causes tremors, stiffness, and difficulties moving, but the condition can also cause hallucinations. Hallucinations affect the senses and can result in people seeing, hearing, feeling, smelling, and tasting things that are not real. Up to 40% of people with Parkinson’s disease experience hallucinations or delusions, and this number increases as the condition progresses....
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First brain marker for an anxiety disorder discovered
by University of Otago Figure 1. Predicted GCSR difference in high anxiety cases. (a) Average GCSR over three classes of anxiolytic drug (ANX, N = 26) compared with placebo (PLA, N = 8). Data are from the same participants as we reported previously39, but with different analysis parameters matching those of the current paper and with...
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Older women, younger men more likely to have uncontrolled blood pressure
DALLAS, Sept. 27, 2021 — Women ages 70 and older and men ages 20-49 were more likely to have uncontrolled hypertension despite taking blood pressure-lowering medications, according to new research presented today at the American Heart Association’s Hypertension Scientific Sessions 2021. The meeting is the premier scientific exchange focused on recent advances in basic and clinical research on...
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Evidence for a neuroprotective effect from transcription factor BCL11A
by University of Bonn Neurons producing the transcription factor BCL11A appear in green. Credit: Marianna Tolve The neurotransmitter dopamine influences the activity of a wide variety of brain areas. A deficiency of this substance can have drastic consequences: The death of dopamine-producing nerve cells in the substantia nigra—a particularly sensitive part of the brain—is what causes...
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Genome “archipelago” as new model of how genomic information influences development and disease
A University at Buffalo team has developed a new model of how information in the genome is organized, called the novel genome archipelago model (GAM). The model provides new insights into how a multitude of interactions among genes may affect normal development as well as mutations that lead to cancer and other diseases. “GAM offers...
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CRISPR screening tool identifies new drug target for leukemia
PHILADELPHIA—A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell. The target, known as ZMYND8, isn’t a mutated gene, rather an epigenetic regulatory protein that cancer cells need...
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VEGF Upregulation Slows Age-Related Capillary Density Loss, Extending Health and Life Span in Mice
The aging of the vasculature has detrimental effects on organs throughout the body. The most structurally apparent issue is that of atherosclerosis, the buildup of fatty deposits that narrow and weaken blood vessels. This ultimately leads to heart failure, stroke, heart attack, and death. A close second is the stiffening of blood vessels, due to a variety of processes such as cross-linking to reduce elasticity in...
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Largest COVID-19 contact-tracing finds children key to spread, evidence of superspreaders
by Morgan Kelly, Princeton University A study of more than a half-million people in India who were exposed to the novel coronavirus SARS-CoV-2, or COVID-19, suggests that the virus’ continued spread is driven by only a small percentage of those who become infected. Furthermore, children and young adults were found to be potentially much more important to transmitting...