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Forsyth researchers demonstrate how changing the stem cell response to inflammation may reverse periodontal disease
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Forsyth researchers demonstrate how changing the stem cell response to inflammation may reverse periodontal disease

FORSYTH INSTITUTE IMAGE: FOR THE STUDY, DR. ALPDOGAN KANTARCI, HIS PHD STUDENT DR. EMMANUEL ALBUQUERQUE, AND THEIR TEAM REMOVED STEM CELLS FROM PREVIOUSLY EXTRACTED WISDOM TEETH AND PLACED THE STEM CELLS ONTO PETRI DISHES. Periodontal disease, also known as gum disease, is a serious infection that affects nearly 50 percent of Americans aged 30 years...

Researchers discover potential cause of immunotherapy-related neurotoxicity
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Researchers discover potential cause of immunotherapy-related neurotoxicity

by Perelman School of Medicine at the University of Pennsylvania New research has uncovered the previously unknown presence of CD19—a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma—in brain cells that protect the blood brain barrier (BBB). This discovery may potentially be the cause...

What to know about Advil and Aleve: Differences and similarities
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What to know about Advil and Aleve: Differences and similarities

Advil and Aleve are two over-the-counter (OTC) medications that belong to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). People may take these drugs to help reduce inflammation and pain or to help control a fever. This article provides information on how Advil and Aleve work and outlines the similarities and differences between them. It also explains how to take each drug safely. What are...

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STUFF ( quercertin) IN CAPERS ACTIVATES KEY PROTEINS IN BRAIN AND HEART

A compound common in pickled capers, quercetin, activates proteins required for normal human brain and heart activity, researchers report. In a new study in Communications Biology, the researchers report that quercetin can directly regulate proteins required for bodily processes such as the heartbeat, thought, muscular contraction, and normal functioning of the thyroid, pancreas, and gastrointestinal...

Study Suggests Method to Starve Pancreatic Cancer Cells
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Study Suggests Method to Starve Pancreatic Cancer Cells

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature Metabolism, also suggest a new potential strategy against pancreatic cancer by identifying critical components of metabolic cross-talk between cells that might be attacked...

Fast-spreading mutation helps common flu subtype escape immune response
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Fast-spreading mutation helps common flu subtype escape immune response

by Johns Hopkins University Bloomberg School of Public Health Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health. The results have implications for flu...

How cells’ ‘lava lamp’ effect could make cancer drugs more powerful
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How cells’ ‘lava lamp’ effect could make cancer drugs more powerful

Discovery that synthetic compounds form concentrated droplets inside cells could shake up drug development — including the hunt for coronavirus treatments. Fluorescently tagged molecules of the cancer drug cisplatin clump up inside droplets in cells.Credit: Isaac Klein/Whitehead Institute There’s a long-standing assumption in the pharmaceutical industry that when drug molecules enter a cell, they spread...

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What the phase 1 trials of the first COVID-19 vaccine really mean

by Sanjay Mishra,  The Conversation Rather than provide a vaccine made from viral proteins, Moderna’s COVID-19 vaccine is composed of synthetic viral mRNA. These molecules are injected into people and cellular protein-making machines, called ribosomes, read and translate the mRNA. It’s these proteins that then trigger an immune response. Credit: The Conversation, CC BY-SA Early morning on...