Pancreatic cancer does not respond to certain anticancer treatments that boost immune responses. A mechanism active in tumour cells that contributes to this evasion of immune targeting has been uncovered. A consistent hallmark of pancreatic cancer is the inability to treat it with immunotherapy — an approach that harnesses the body’s immune response to target...
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Exploring cells’ path to build cholesterol and finding a future drug target
Researchers based at UTokyo and RIKEN in Japan, and the University of New South Wales in Australia have uncovered a new aspect of one of the molecules involved in cells’ production line to build cholesterol. This understanding could provide a new target for high-cholesterol medications and other drugs that kill pests like athlete’s foot fungus...
Tracking down ‘illegal parkers’ in cancer cells
by Kristian Lozina, University of Würzburg Squamous cell carcinoma is a very unusual type of cancer. It occurs in many tissues—for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin. Due to the many mutations in this type of cancer, treatment is a particularly challenging task for medicine. However, all squamous...
Immunotherapy combo effective for patients with high-grade neuroendocrine cancer
by SWOG Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial. Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy...
Diabetes in mice cured rapidly using human stem cell strategy
Researchers have converted human stem cells into insulin-producing cells and demonstrated in mice infused with such cells that blood sugar levels can be controlled and diabetes functionally cured for nine months. The findings, from researchers at Washington University School of Medicine in St. Louis, are published online in the journal Nature Biotechnology. “These mice had...
New study shows significant increase in weight after breast cancer
Earlier weight gain prevention and management needed NICM HEALTH RESEARCH INSTITUTE, WESTERN SYDNEY UNIVERSITY New study findings suggest that weight gain after breast cancer is a greater problem than previously thought. The first national survey on weight after breast cancer in Australia, published in BMC Cancer journal, found close to two-thirds (63.7%) of women reported...
Contact Lenses, Skin Patches, Tatoo Inks Exposed to UV Change Color to Warn of Exposure
FEBRUARY 6TH, 2020 MEDGADGET EDITORS MATERIALS Exposure to ultraviolet (UV) light can lead to the development of skin cancers, so limiting how much time one spends under the Sun’s rays and using sunscreen when necessary is critically important. Currently, there are few tools available that notify users of their UV exposure, especially those that are...
YOUNG PEOPLE WITH DIABETES ARE 3X MORE LIKELY TO ATTEMPT SUICIDE
FABIENNE LANDRY-MCGILL “Having a chronic illness like diabetes adds complexity to this stage in a very challenging way.” The risks of psychiatric disorders and suicide attempts are substantially higher for young people from 15 to 25 years old with type 1 diabetes, a new study shows. Researchers looked at the risk of psychiatric disorders in...
Discovery sheds new light on how cells move
When we cut our skin, groups of cells rush en masse to the site to heal the wound. But the complicated mechanics of this collective cell movement — which are facilitated by rearrangements between each cell and its neighbors — have made it challenging for researchers to decipher what’s actually driving it. “If we can...
Novel artificial intelligence algorithm helps detect brain tumor
By Angela Betsaida B. Laguipo, BSN A brain tumor is a mass of abnormal cells that grow in the brain. In 2016 alone, there were 330,000 incident cases of brain cancer and 227,000 related-deaths worldwide. Early detection is crucial to improve patient prognosis, and thanks to a team of researchers, they developed a new imaging...