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Early screening based on family history may have dramatic effects on colorectal cancer detection
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Early screening based on family history may have dramatic effects on colorectal cancer detection

by Wiley In an analysis that included information on adults diagnosed with colorectal cancer between 40 and 49 years of age, almost all patients could have been diagnosed earlier if they had been screened according to current family history-based screening guidelines. The findings are published early online in Cancer, a peer-reviewed journal of the American...

A Guide to Biosimilar Prices: How Much They Cost and How You Can Save
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A Guide to Biosimilar Prices: How Much They Cost and How You Can Save

by Lauren Chase Biosimilars have made a lot of headway in the pharmaceutical world over the past few years. While they’ve been hailed for their cost-saving potential, many have failed to take hold in the U.S. market. Leaders in healthcare have claimed that the regulatory systems in place will make biosimilars too expensive to continue...

Ultraviolet LEDs prove effective in eliminating coronavirus from surfaces and, potentially air and water
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Ultraviolet LEDs prove effective in eliminating coronavirus from surfaces and, potentially air and water

As COVID-19 continues to ravage global populations, the world is singularly focused on finding ways to battle the novel coronavirus. That includes the UC Santa Barbara’s Solid State Lighting & Energy Electronics Center (SSLEEC) and member companies. Researchers there are developing ultraviolet LEDs that have the ability to decontaminate surfaces—and potentially air and water—that have...

How a Premier U.S. Drug Company Became a Virus ‘Super Spreader’
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How a Premier U.S. Drug Company Became a Virus ‘Super Spreader’

By: Kim Barker is an enterprise reporter BOSTON — On the first Monday in March, Michel Vounatsos, chief executive of the drug company Biogen, appeared in good spirits. The company’s new Alzheimer’s drug was showing promise after years of setbacks. Revenues had never been higher. Onstage at an elite health care conference in Boston, Mr....

Pancreatic cancer hidden in plain sight
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Pancreatic cancer hidden in plain sight

Pancreatic cancer does not respond to certain anticancer treatments that boost immune responses. A mechanism active in tumour cells that contributes to this evasion of immune targeting has been uncovered. A consistent hallmark of pancreatic cancer is the inability to treat it with immunotherapy — an approach that harnesses the body’s immune response to target...

Exploring cells’ path to build cholesterol and finding a future drug target
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Exploring cells’ path to build cholesterol and finding a future drug target

Researchers based at UTokyo and RIKEN in Japan, and the University of New South Wales in Australia have uncovered a new aspect of one of the molecules involved in cells’ production line to build cholesterol. This understanding could provide a new target for high-cholesterol medications and other drugs that kill pests like athlete’s foot fungus...

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Tracking down ‘illegal parkers’ in cancer cells

by Kristian Lozina, University of Würzburg Squamous cell carcinoma is a very unusual type of cancer. It occurs in many tissues—for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin. Due to the many mutations in this type of cancer, treatment is a particularly challenging task for medicine. However, all squamous...

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Immunotherapy combo effective for patients with high-grade neuroendocrine cancer

by SWOG Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial. Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy...

Diabetes in mice cured rapidly using human stem cell strategy
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Diabetes in mice cured rapidly using human stem cell strategy

Researchers have converted human stem cells into insulin-producing cells and demonstrated in mice infused with such cells that blood sugar levels can be controlled and diabetes functionally cured for nine months. The findings, from researchers at Washington University School of Medicine in St. Louis, are published online in the journal Nature Biotechnology. “These mice had...