by Atrium Health Wake Forest Baptist Credit: JCI Insight (2023). DOI: 10.1172/jci.insight.162454 It’s well-known that people with type 2 diabetes are at an increased risk of developing Alzheimer’s disease, but the reason why isn’t fully understood and is an area of current research. Now, scientists at Wake Forest University School of Medicine have uncovered a novel mechanism...
HEINRICH-HEINE UNIVERSITY DUESSELDORF IMAGE: THE AI-BASED ESP MODEL DEVELOPED AT HHU CAN BE USED TO PREDICT WHICH SUBSTRATES CAN BE CONVERTED BY ENZYMES. CREDIT: HHU – PAUL SCHWADERER / STOCK.ADOBE.COM – PETARG Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult...
by German Cancer Research Center Weight Change Among Cases and Controls Within 12 Years Before Diagnosis/Interview Lower and upper hinges correspond to 25th and 75th quantile of weight changes, respectively; lower and upper whiskers correspond to 5th and 95th quantile, respectively; outliers not shown. Credit: JAMA Network Open (2023). DOI: 10.1001/jamanetworkopen.2023.9556 Obesity is a known risk factor for...
Two of the patients showed a surge of gamma wave activity, considered the fastest brain activity and associated with consciousness. Photograph: Deco/AlamyDeath and dying People in comas showed ‘conscious-like’ brain activity as they died, study says ‘Potential neuro-signatures of consciousness’ observed in unresponsive patients at time of death, scientists sayHannah Devlin Science correspondent@hannahdevMon 1 May 2023 15.00...
by University College London Study infographic leveraging neural network analysis of biventricular CMR data and GWAS to prioritize plasma proteins with an effect on cardiac outcomes. CMR, cardiac magnetic resonance imaging (MRI); GWAS, genome-wide association study. Credit: Science Advances (2023). DOI: 10.1126/sciadv.add4984 Modern drugs can be very effective at treating cancer and have led to greatly improved survival...
by University College Dublin 3D render of the tibias treated with the current clinical treatment option chemotherapeutics or treated with chemotherapeutics plus gene therapy. Post-treatment there is significantly more bone (purple) present following treatment with the novel therapeutics. Credit: Created with Biorender.com. New research has identified a potential therapeutic target and developed a unique delivery system...
H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. — MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes. Deregulation of MYC proteins occurs in more than half of all cancers and is associated with poor patient prognosis and...
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