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Testing for just three genes could help prevent 75% of avoidable side effects for certain medications

by Queen Mary, University of London Credit: Pixabay/CC0 Public Domain A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent on the patient’s genes. Of this subset of ADRs, 75%...

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Genetic bias in cells: Why some genes favor mom or dad, and what it means for disease outcomes

by Alan Dove, Columbia University Irving Medical Center Ex vivo clonally expanded primary T cells used for detection of aRMAE. Credit: Nature (2025). DOI: 10.1038/s41586-024-08346-4 New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. ADVERTISING Every biology student learns that...

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Large-scale genetic study identifies 14 genes linked to neuroticism

by Ingrid Fadelli , Medical Xpress Study overview. Credit: Nature Human Behaviour (2024). DOI: 10.1038/s41562-024-02045-w Neuroticism is a key personality trait described by well-established psychological theories, associated with a tendency towards emotional instability and negative emotions. Past studies found that this personality trait often goes hand in hand with various mental health disorders, as well as some...

MRI may lower breast cancer deaths from variants in 3 genes
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MRI may lower breast cancer deaths from variants in 3 genes

by University of Washington School of Medicine This screening MRI detected a very small cancer (circled) in the patient’s breast. Credit: Dr. Kathryn Lowry, Radiology, UW Medicine Annual MRI screenings starting at ages 30 to 35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes, according...