Tag: <span>acute leukemia</span>

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Cracking cancer’s code: Research identifies novel drug target for acute myeloid leukemia treatment

by Claire Kowalick, University of Texas Health Science Center at San Antonio Graphical abstract. Credit: Cell Stem Cell (2025). DOI: 10.1016/j.stem.2025.01.010 Despite advances in cancer treatment in recent years, five-year survival rates for acute myeloid leukemia (AML) remain low at just 30% on average, according to the National Cancer Institute. Factors in the development of AML are diverse...

Researchers revisit potent drug as promising treatment for acute leukemia
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Researchers revisit potent drug as promising treatment for acute leukemia

by National University of Singapore Chemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compounds from 3 chemical libraries, a negative control (dimethyl sulfoxide [DMSO]) and a positive control (THZ1), were added to Jurkat cells that stably expressed the GIMAP enhancer reporter construct....