by Zhang Nannan, Chinese Academy of Sciences Neural cell competition in development, homeostasis and disease. Credit: Gao Lisen In a recently published review, researchers led by Prof. Wu Qingfeng at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences explored the ongoing process of neural cell competition (NCC), a fundamental mechanism that...
Tag: <span>Aging</span>
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Aging and Disease | Insilico unveils a robotics lab-driven study highlighting TNIK inhibition as a promising anti-aging strategy
Peer-Reviewed Publication InSilico Medicine FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail video: Using an AI-driven robotics laboratory , the team identified INS018_055 (Rentosertib) —a potent small-molecule TNIK previously developed by Insilico Medicine, which has already advanced into clinical trials for idiopathic pulmonary fibrosis (IPF)—as a highly effective senomorphic agent capable of mitigating cellular senescence.view more Credit: Insilico Medicine A groundbreaking study led...
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Reversing aging: Are billionaires throwing cash at the wrong target?
By Rich Haridy February 02, 2025 Several multi-billion dollar startups are racing to develop anti-aging medicines but are they looking in the wrong place? Depositphotos View 1 Images In late 2021 a Russian-born billionaire named Yuri Milner gathered some of the most celebrated scientific minds of our time at his lavish US$100-million-dollar mansion in California. The topic of...
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Why our biological clock ticks: Research reconciles major theories of aging
Two prominent explanations for aging are not so different after all; results call current anti-aging strategies into questionPeer-Reviewed Publication University of California – San Diego FacebookXLinkedInWeChatBlueskyMessageWhatsAppEmail image: Using patient data from several banks of genomics data, researchers at UC San Diego were able to make similar predictions of aging using either mutations or epigenetic modifications....
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Aging changes some brain cells more than others
By Paul McClure January 02, 2025 Certain brain cells respond to aging differently than others DALL-E View 3 Images View gallery – 3 images Detailed mapping of 1.2 million brain cells has revealed that not all cell types age in the same way and that some – found in a specific ‘hot spot’ – are more...
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Cerebral blood flow and arterial transit in older adults
ATT may be more sensitive to age-related decline than CBF, and therefore useful for early detection and management of cerebrovascular impairment.”Peer-Reviewed Publication Impact Journals LLC Figure 4. Flow chart of the screening and experimental sessions. Abbreviations: MoCA: Montreal Cognitive Assessment; ECG: electrocardiogram; MRI: magnetic resonance imaging; CBF: cerebral blood flow; ATT: arterial transit time; GMV: grey matter...
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Out with the old, in with the new: the science behind memory clutter and aging
News Release 17-Sep-2024 Boston University researchers uncover how memory maintenance and deletion shape cognitive decline in aging Peer-Reviewed PublicationBoston University Ever feel like those catchy song lyrics or random pieces of trivia won’t leave your head, and it’s affecting your memory? Boston University associate professor of psychological & brain sciences Dr. Rob Reinhart, along with...
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Not just a normal part of aging: Dizziness in older adults is linked to higher risk of future falls
September 18, 2024 by Imperial College London Credit: Pixabay/CC0 Public DomainThe first meta-analysis of its kind has shown a conclusive link between older adults experiencing spells of dizziness and a dramatically elevated risk of falling. The study, “Association between dizziness and future falls and fall-related injuries in older adults: a systematic review and meta-analysis,” is...
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Small RNA molecule plays role in driving aging, research confirms
September 11, 2024 by Kendall Daniels, University of North Carolina at Chapel Hill School of Medicine The liver of miR-29TG and 2 year-old wildtype mice share changes in key aging-related genes and pathways. Credit: Communications Biology (2024). DOI: 10.1038/s42003-024-06735-zA team led by UNC School of Medicine researchers is the first to confirm that a small...
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The Molecular Secret to Longevity: Scientists Have Discovered a “Lifespan Limit Line”
By Eötvös Loránd University September 8, 2024 Scientists have identified a “mitochondrial epigenetic clock” involving 6mA in mtDNA, which may revolutionize aging research by providing new insights into lifespan regulation and potential interventions for healthier aging.Building on their groundbreaking research in epigenetics and transposable elements related to aging, scientists at Eötvös Loránd University have achieved...