by British Medical Journal Credit: Pixabay/CC0 Public Domain Frequent use of antibiotics may heighten the risk of inflammatory bowel disease—Crohn’s disease and ulcerative colitis—among adults over 40, suggests research published online in the journal Gut. The risk seems to be cumulative and greatest 1-2 years after use and for those antibiotics targeting gut infections, the findings indicate. Mounting...
Tag: <span>antibiotics</span>
Developing antibiotics that target multiple-drug-resistant bacteria
HOKKAIDO UNIVERSITY IMAGE: THE SPHAERIMICIN ANALOGS (SPMS) INHIBIT THE ACTIVITY OF MRAY, AND HENCE THE REPLICATION OF BACTERIA, WITH DIFFERENT DEGREES OF EFFECTIVENESS. THE POTENCY OF THE ANALOG INCREASES AS THE IC50 DECREASES (TAKESHI NAKAYA, ET AL. NATURE COMMUNICATIONS. DECEMBER 20, 2022). CREDIT: (TAKESHI NAKAYA, ET AL. NATURE COMMUNICATIONS. DECEMBER 20, 2022) Researchers have designed...
Study suggests reducing use of broad-spectrum antibiotics for acute kidney infections
by Ochsner Health System Credit: Unsplash/CC0 Public Domain A new study led by Ochsner infectious diseases clinical pharmacist Kevin Lin, PharmD, was recently published in PLoS One, suggesting that oral cephalosporins are as safe and effective as the standard of care fluoroquinolones (FQs) for the treatment of acute kidney infections. Cephalosporins belong to a family of...
Stealth-care system: Scientists test ‘smart’ red blood cells to deliver antibiotics that target specific bacteria
MCMASTER UNIVERSITY IMAGE: SCIENTISTS TEST ‘SMART’ RED BLOOD CELLS TO DELIVER ANTIBIOTICS THAT TARGET SPECIFIC BACTERIA CREDIT: ELLA MARUSHCHENKO Physicists at McMaster University have identified a natural delivery system which can safely carry potent antibiotics throughout the body to selectively attack and kill bacteria by using red blood cells as a vehicle. The platform, described...
Novel technique helps discover whether bacteria that cause meningitis are resistant to antibiotics
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: IT CAN BE USED TO STUDY THE RESISTANCE PROFILE OF PNEUMOCOCCUS EVEN IN THE ABSENCE OF THE ISOLATED STRAINS (PNEUMOCOCCI OBSERVED IN THE MICROSCOPE) CREDIT: IVANA CAMPOS A study published in the journal PLOS ONE could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae,...
No antibiotics worked, so this woman turned to a natural enemy of bacteria to save her husband’s life
By Sandee LaMotte, CNNUpdated 9:56 AM EDT, Fri July 08, 2022 (CNN)In February 2016, infectious disease epidemiologist Steffanie Strathdee was holding her dying husband’s hand, watching him lose an exhausting fight against a deadly superbug infection. After months of ups and downs, doctors had just told her that her husband, Tom Patterson, was too rackedwith...
Most patients with appendicitis can be treated with antibiotics
UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES FINDINGS Outpatient antibiotic management of selected patients with appendicitis is safe, allowing many patients to avoid surgery and hospitalization, and should be considered as part of shared decision-making between doctor and patient. Of 726 participants who were randomized to receive antibiotics, 46% were discharged from the emergency...
How bacteria adhere to cells: Basis for the development of a new class of antibiotics
GOETHE UNIVERSITY FRANKFURT FRANKFURT. The adhesion of bacteria to host cells is always the first and one of the decisive steps in the development of infectious diseases. The purpose of this adhesion by infectious pathogens is first to colonize the host organism (i.e., the human body), and then to trigger an infection, which in the...
Antibiotics wreak havoc on athletic performance
by University of California – Riverside 10 days of antibiotics reduced the adult gut microbiome from millions of aerobic colony-forming units to a non-detectable amount. Credit: Monica McNamara/UCR New research demonstrates that by killing essential gut bacteria, antibiotics ravage athletes’ motivation and endurance. The UC Riverside-led mouse study suggests the microbiome is a big factor...
Could the ‘glue’ bees use to seal hives boost power of antibiotics?
By MAX AITCHISON FOR THE MAIL ON SUNDAY A ‘glue’ that bees use to seal their hives and fight infection could hold the key to boosting the waning power of antibiotics, according to a pioneering study. ‘Bee glue’, or propolis, is a biscuity-brown, sticky substance that honey bees produce when building their hives. It is made...