Vaccines are notoriously difficult to transport to remote or dangerous places, as they spoil when not refrigerated. Formulations are safe between 2°C and 8°C, but at other temperatures the proteins start to unravel, making the vaccines ineffective. As a result, millions of children around the world miss out on life-saving inoculations. However, scientists have now...
As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach – identifying neutralizing antibodies that could be used as a...
by Qian Ye and Matthew Knight A Chinese laboratory has been developing a drug it believes has the power to bring the coronavirus pandemic to a halt. The outbreak first emerged in China late last year before spreading across the world, prompting an international race to find treatments and vaccines. A drug being tested by...
by Ecole Polytechnique Federale de Lausanne Vaccines are one of the most effective interventions to prevent the spreading of infectious diseases. They trigger the immune system to produce antibodies that protect the body against infection. However, we still lack efficacious vaccines for many important pathogens like the flu or dengue fever. “When a vaccine doesn’t...
An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases. The scientists compared the most common inherited form of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) with a rarer disease called spinocerebellar ataxia type 36 (SCA36). Both of the diseases are caused by abnormally expanded and...
By JENNIFER SMITH FOR DAILYMAIL.COM Researchers in San Francisco and some in Massachusetts studied 14 different antibody tests Among them, only three returned results that were more than 99% specific in detecting antibodies One test, made by Sure Biotech which is registered in both the US and Hong Kong, had a 100% accuracy rate The...
Nature wades through the literature on COVID-19 so you don’t have to. 28 April — ‘Dry swabbing’ offers a workaround to test-chemical scarcity Wide-scale genetic testing for SARS-CoV-2 has been hampered, in part, by shortages of the solutions used to store sampling swabs and extract viral RNA from them. To overcome this difficulty, a team...
by Brown University Researchers have discovered a promising new strategy for combating malaria, a mosquito-borne parasite that claims nearly a half-million lives each year. For a study reported in the journal Nature, researchers screened blood samples from children who had natural immune resistance to severe malaria infection. The study identified an antibody to a particular...
by Queen Mary, University of London Mice with high levels of this protein were also found to exhibit behaviours that are characteristic of anxiety and stress, such as digging and excessive grooming. When the researchers treated the mice with an antibody that neutralised Imood, the animals’ anxiety levels reduced. The findings have led the researchers...
Study by the University of Bonn may enable new therapies against certain forms of the disease UNIVERSITY OF BONN Certain forms of epilepsy are accompanied by inflammation of important brain regions. Researchers at the University of Bonn have now identified a mechanism that explains this link. Their results may also pave the way to new...
