by Ludwig Maximilian University of Munich Salicylate suppresses viability and proliferation of CRC cells independent of p53. A Cell viability of HCT116 cells was determined by MTT assay after treatment with indicated concentrations of salicylate for 48 h. IC50 was determined using GraphPad Prism based on changes in viability. B Cell viability of non-transformed CCD-18-Co and HCEC-1CT...
By Giri Viswanathan, CNN New research re-evaluates aspirin’s role in long-term treatment plans for patients with stents.Grace Cary/Moment RF/Getty ImagesCNN — For some high-risk cardiovascular patients with stents, the often-recommended practice of prolonged taking of aspirin might be ineffective, and in some cases, even harmful, a new study found. The report, published in the scientific journal...
by Washington University School of Medicine Aspirin can help prevent a second heart attack, but most don’t take itWorldwide, only 40% of eligible patients are taking daily aspirin to prevent a second heart attack or stroke, according to a new study led by Washington University School of Medicine in St. Louis. Grouped by per-capita income,...
Walter Alexander June 01, 2023 CHICAGO – The regular use of aspirin or other nonsteroidal anti-inflammatory drugs was found to be associated with a lower risk of early-onset conventional and advanced adenomas. The authors say that aspirin could prove to be an effective strategy in preventing early-onset colorectal cancer cases. “What we have here is a 15% reduction for...
By Paul McClure February 26, 2023 A new study suggests that genetic susceptibility to ovarian cancer does not affect the protective effect of aspirin in reducing ovarian cancer risk Depositphotos Ovarian cancer is a highly fatal type of cancer that can be caused by several genetic factors. A recent study examined whether the protection provided...
Richard Mark Kirkner February 15, 2023 A new meta-analysis has added evidence questioning the utility and efficacy of prophylactic low-dose aspirin for preventing cardiovascular events in people who don’t have atherosclerotic cardiovascular disease (ASCVD), whether or not they’re also taking statins, and finds that at every level of ASCVD risk the aspirin carries a risk of major bleeding that exceeds its...
by University of Maryland School of Medicine Credit: Unsplash/CC0 Public Domain Patients who have surgery to repair bone fractures typically receive a type of injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots, but a new clinical trial found that over-the-counter aspirin is just as effective. The findings, presented today at the Orthopedic Trauma Association (OTA)...
by University of Maryland School of Medicine Credit: Unsplash/CC0 Public Domain Patients who have surgery to repair bone fractures typically receive a type of injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots, but a new clinical trial found that over-the-counter aspirin is just as effective. The findings, presented today at the Orthopedic Trauma...
by University of California, Irvine A schematic illustrating the mathematical model. The six cell types are denoted by circles, the mutation rates that give rise to different types are marked by the straight arrows. Type 6 (late adenoma) is marked in red. Crypt conversion rates are indicated by circular arrows and crypt fission by multiple...
(HealthDay)—Regular aspirin use does not improve invasive disease-free survival (iDFS) among high-risk breast cancer patients with human epidermal growth factor receptor 2 (HER2)-negative disease, according to a study presented Feb. 15 as part of the American Society for Clinical Oncology Plenary Series. Wendy Y. Chen, M.D., M.P.H., from the Dana Farber Cancer Institute in Boston,...
