A multi-institution international team led by researchers at Baylor College of Medicine has developed a new strategy to overcome one of the main obstacles to the treatment of brain cancer—access to the tumor. Under the influence of cancer, the blood-brain barrier diverts immune T cells that attempt to enter the brain to fight the tumor....
Tag: <span>Brain cancer</span>
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Misregulated protein breakdown promotes leukemias and brain cancer
An enzyme that is responsible for the breakdown of specific amino acids in food plays a key role in the development of leukemias and brain cancer, according to scientists from the German Cancer Research Center (DKFZ) in Heidelberg. They have reported their findings in Nature. The researchers have discovered a surprising link between energy metabolism and...
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Brain cancer vaccine effective in some patients
Most people with the deadly brain cancer glioblastoma die less than 18 months after diagnosis. But a multicenter clinical trial of a personalized vaccine that targets aggressive cancer has indicated improved survival rates for such patients. The study appears May 29 in the Journal of Translational Medicine. The phase three clinical trial included 331 patients at over 80 sites...
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Cancer trial led by University of Minnesota Medical School’s Dr. Clark Chen shows promise
New data illustrates notable success in treatment of recurrent brain cancer MINNEAPOLIS – October 27, 2017 – New data from a Phase I clinical trial led by Clark Chen, M.D., Ph.D., Lyle French Chair in Neurosurgery and Head of the University of Minnesota Medical School Department of Neurosurgery shows more than a quarter of patients...
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Zika virus could be used to treat brain cancer patients, study suggests
Recent outbreaks of Zika virus have revealed that the virus causes brain defects in unborn children. But in a study to be published September 5 in The Journal of Experimental Medicine, researchers from Washington University School of Medicine in St. Louis and the University of California, San Diego report that the virus could eventually be used...
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What are ketogenic diets? Can they treat epilepsy and brain cancer?
Ketogenic diets are back in the news with claims they are a “cure-all”. Research shows that in epilepsy not controlled by current treatment, around 50% of children and adults following ketogenic diets have a reduction in seizures. For brain cancer, most research has been in animals. A number of human trials are underway testing safety, tolerance, interactions with other treatments, side-effects and the impact on...
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Study highlights new link between gene fusion and bladder and brain cancer
• Previously overlooked section of fusion found to worsen cancer cells • Scientists find section acts like a vacuum cleaner ‘hoovering up’ healthy parts of cell • Preventing’ signalling’ in cells may not stop cancer in studied gene fusion A study by the University of Warwick sheds new light on gene fusion in bladder and...
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New brain cancer drug targets revealed
Researchers from Case Western Reserve University School of Medicine and The Cleveland Clinic designed a way to screen brain tumor cells and identify potential drug targets missed by other methods. The team successfully used their technique to find a glioblastoma cancer gene that, when blocked, extends mouse survival rates. In a study published in Nature, the...
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Can olive oil prevent brain cancer? Key nutrient in the staple Mediterranean ingredient stops tumour-causing cells from functioning
The compound, known as oleic acid, indirectly prevents brain cancer formation Oleic acid inhibits a protein that hinders the production of a molecule – miR-7 miR-7 is a cell molecule that is known to suppress tumour formation in the brain It is unclear whether adding olive oil to your diet could reduce brain cancer risk...
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Cold virus, stem cells tested to destroy deadly brain cancer
Killer T cells surround a cancer cell. A first-of-a-kind neural stem cell therapy that works with a common cold virus to seek out and attack a lethal and aggressive brain cancer is being tested at Northwestern Medicine in a Phase I clinical trial for patients newly diagnosed with malignant glioma. The novel drug to...