by University of Leicester Maintenance of the immune microenvironment in BC-PDEs. Whole slide mIF-stained sections of BC-PDEs were digitized using a Vectra Polaris and analyzed in InForm. (A) Representative image of a single PDE stained for CD4, CD8, FOXP3, CK and DAPI. (B) Individual cells were phenotyped into T-Helper (CD4 + ve), T-effector (CD8 + ve), T-regulatory (CD4 + ve FOXP3 + ve), Tumor...
Tag: <span>Breast Cancer</span>
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Mini-tumors from circulating breast cancer cells offer new treatment insights
by German Cancer Research Center Credit: Unsplash/CC0 Public Domain Tumor cells circulating in the blood are the germ cells of breast cancer metastases. They are very rare and have not been propagated in the culture dish until now, which made research into therapy resistance difficult. ADVERTISING A team from the German Cancer Research Center (DKFZ), the...
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AI-powered blood test spots earliest breast cancer signs
A new screening method that combines laser analysis with a type of AI is the first of its kind to identify patients in the earliest stage of breast cancer, a study suggests. The fast, non-invasive technique reveals subtle changes in the bloodstream that occur during the initial phases of the disease, known as stage 1a,...
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1 GENE MAY PUT YOU AT HIGHER RISK OF BREAST CANCER’S SPREAD
DECEMBER 10TH, 2024POSTED BY KATHERINE FENZ-ROCKEFELLER (Credit: Getty Images) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY ROCKEFELLER UNIVERSITY Researchers have discovered a genetic predisposition that increases the risk of breast cancer metastasis. Ninety percent of cancer deaths are due to the spread of cancer, not complications from the original...
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Estrous rhythm found crucial for optimizing breast cancer therapy
by Justin Jackson, Medical Xpress Oestrous cycle-dependent proliferation of tumor cells during oestrus stage in MMTV-PyMT tumors. Credit: Nature (2024). DOI: 10.1038/s41586-024-08276-1 The Netherlands Cancer Institute has found that the estrous cycle stage significantly influences mammary tumors’ sensitivity to chemotherapy. In mouse models of breast cancer, treatment initiated during the diestrus stage resulted in reduced responses to...
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Hair growth drug safe at low doses for breast cancer patients
Peer-Reviewed Publication NYU Langone Health / NYU Grossman School of Medicine Hair loss during chemotherapy can cause enough distress for some women to lose self-confidence, which experts say may discourage them from seeking chemotherapy in the first place. Oral minoxidil is a commonly prescribed treatment for hair loss. The drug is also the active ingredient...
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DAPK3 emerges as a new regulator of migration of triple-negative breast cancer cells
Graphic representation of the functional role of DAPK3 in TNBC cells. Credit: PNAS Nexus (2024). DOI: 10.1093/pnasnexus/pgae401 Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone. They experience worse outcomes than patients with other...
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Study confirms fibrosis as a prognostic indicator in the most common breast cancer
September 19, 2024 by The Spanish National Cancer Research Centre Histological slide of cancerous breast tissue. The pink “riverways” are normal connective tissue, and the blue is cancer cells. Credit: Cecil Fox, National Cancer Institute (NIH).The most common breast cancer is HER2-negative, so called because it has low amounts of one of the proteins that...
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Breast cancer rises among Asian American and Pacific Islander women
September 9, 2024 by Phillip Reese, KFF Health News Credit: Pixabay/CC0 Public DomainAbout 11,000 Asian American and Pacific Islander women were diagnosed with breast cancer in 2021 and about 1,500 died. The latest federal data shows the rate of new breast cancer diagnoses in Asian American and Pacific Islander women—a group that once had relatively...
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Fewer than 3 of 10 women cite diet when asked how to reduce chances of breast cancer
News Release 26-Aug-2024 Nationwide survey preceding breast cancer awareness month also shows lack of knowledge of protective benefits of soy and harmful effects of dairy Reports and ProceedingsPhysicians Committee for Responsible Medicine WASHINGTON, D.C. ؚ— Just 28% of U.S. women are aware that a healthful diet can lower the risk of developing breast cancer, according...