Existing immunotherapy drugs could help some breast cancer patients, based on the genetic changes in their tumors Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumours, researchers at the Wellcome Trust Sanger Institute and their collaborators find. Published today (13 September) in Cancer Research, scientists identify particular genetic changes...
Tag: <span>Breast Cancer</span>
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Z-endoxifen shows promise as new treatment for common breast cancer type
Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease. This finding was reported from a clinical trial conducted by researchers at Mayo Clinic and the National Cancer Institute, and published in the Journal of Clinical Oncology. The final...
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How a chemo drug can help cancer spread from the breast to the lungs
COLUMBUS, Ohio -The very same treatment that thwarts breast cancer has a dark side—it can fuel the spread of the disease to the lungs. Researchers at The Ohio State University studied the cascade of events that lead to metastatic cancer and found clues to why it happens, opening up the possibility of one day interfering with the...
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Hormone replacement therapies help breast cancer grow, spread
Hormone replacement therapies could cause specialized cancer cells to induce growth, metastasis Hormone replacement therapies, or medications containing female hormones that substitute those no longer produced by the body, often are prescribed to reduce the effects of menopausal symptoms in women. Research has indicated that women who take hormone replacement therapies have a higher incidence...
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A simple breath test could be the next step in diagnosing breast cancer
The USC Norris Comprehensive Cancer Center is recruiting people for a clinical trial that will research the effectiveness of a breath test for breast cancer diagnostics. The BreathLink device captures a two-minute sample of a patient’s breath and provides prompt results on whether there are indications of breast cancer. If proven effective, the test would...
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Chemotherapy before breast cancer surgery might fuel metastasis
When breast cancer patients get chemotherapy before surgery to remove their tumor, it can make remaining malignant cells spread to distant sites, resulting in incurable metastatic cancer, scientists reported last week. The main goal of pre-operative (neoadjuvant) chemotherapy for breast cancer is to shrink tumors so women can have a lumpectomy rather than a more...
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Tumor Test Helps Identify Which Breast Cancers Don’t Require Extra Treatment
For years, doctors have focused on detecting breast cancer at the earliest possible moment after a tumor develops so treatment can start right away. But more and more studies are showing many small, early tumors don’t present a danger. So, when is it safe to remove a tumor but skip additional treatments like tamoxifen, chemotherapy...
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A protein that stem cells require could be a target in killing breast cancer cells
Researchers have discovered that a chromatin-regulating protein called BPTF must be present for stem cells in the breast to perform their normal functions — maintaining a supply of stem cells and seeding the breast with specialized new …more For years, cancer experts have realized that cancerous cells behave in certain ways like stem cells, unspecialized...
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Study identifies RNA molecule that shields breast cancer stem cells from immune system
Researchers from Princeton University’s Department of Molecular Biology have identified a small RNA molecule that helps maintain the activity of stem cells in both healthy and cancerous breast tissue. Above, the microscopic image shows …more Researchers from Princeton University’s Department of Molecular Biology have identified a small RNA molecule that helps maintain the activity of...
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Cancer Is Partly Caused By Bad Luck, Study Finds
Nearly two-thirds of cell mutations that cause cancer are caused by random error, a study found. Cancer can be caused by tobacco smoke or by an inherited trait, but new research finds that most of the mutations that lead to cancer crop up naturally. The authors of the study published Thursday poked a hornet’s nest by suggesting...